Results 151 to 160 of about 13,806,711 (306)
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
QSAR Models for Climate Impact Assessment: Born to Be Sustainable. [PDF]
Sgariboldi A, Chirico N, Papa E.
europepmc +1 more source
Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers
Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui +4 more
wiley +1 more source
Report of the Impact Assessment and Evaluation Group to the CGIAR Mid Term Meeting 1997
Third report of the Impact Assessment and Evaluation Group (IAEG) to the CGIAR, presented at the CGIAR Mid Term Meeting, May 1997. It presents the work of the group over its first 18 months of existence, and requests comments from the CGIAR on its ...
CGIAR Impact Assessment and Evaluation Group
core
A Bias-Corrected HighResMIP Dataset for Impact Assessment Studies. [PDF]
Yakubu F +3 more
europepmc +1 more source
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil +3 more
wiley +1 more source
Terrestrial Ecotoxicity of Plastics: Effect Factors for Life Cycle Impact Assessment. [PDF]
Galafton C +3 more
europepmc +1 more source
Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux +7 more
wiley +1 more source
Report of the Impact Assessment and Evaluation Group to CGIAR International Centers Week 1998
Report of the Impact Assessment and Evaluation Group (IAEG) to CGIAR International Centers Week 1998. The report reprints the terms of reference of the IAEG, and its strategy to build capacity for impact assessment among IARCs and NARS. It discusses IARC
CGIAR Impact Assessment and Evaluation Group
core

