Results 161 to 170 of about 536,512 (312)
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
Post-Impact Behaviour of Pseudo-Ductile Thin-Ply Angle-Ply Hybrid Composites. [PDF]
Prato A +3 more
europepmc +1 more source
Exploring the relationship between land-use system and travel behaviour - some first findings [PDF]
Theories on the reciprocal relationship between land-use and transport address changes in locational decisions and travel behavior of private actors (households and firms) due to alternations in the transport system, respectively land-use system ...
Veronique Van Acker, Frank Witlox
core
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
The Impact of Media on Consumers’ Environmental Behaviour
People, companies and society are becoming more mindful about the environment, and thus the market demand environmentally-sustainable merchandises and services. Today consumers act more pro-environmentally, as in the past decades they have changed their behaviour.
openaire +2 more sources
Compression after Impact Behaviour and Failure Analysis of Nanosilica-Toughened Thin Epoxy/GFRP Composite Laminates. [PDF]
Lal LPJ +4 more
europepmc +1 more source
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Managing challenging behaviour in the classroom is a problem faced by all teachers. Challenging behaviour is any form of behaviour that interferes with children's learning or normal development; is harmful to the child, other children or adults; or puts ...
Langley, Dene John
core

