Results 61 to 70 of about 14,048,705 (249)

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Impact Competence Catalogue

This tool presents a selection of competences that are relevant for societal impact. The content is presented as a non-exhaustive list of competences that academics can develop for impact-oriented academic activities.
Evaluating Societal Impact
core   +1 more source

Drivers and barriers to the diffusion of energy-efficient technologies—a plant-level analysis of the German steel industry [PDF]

, 2017
The paper aims at explaining why large-scale energy-intensive industries—here the German iron and steel industry—had a period of slow uptake of major energy-efficient technologies from the mid 1990s to mid 2000s (Arens and Worrell, 2014) and why from the
Sustainable Energy, Eichhammer, Wolfgang, Energy, Resources & Technological Change, Energy and Resources, Arens, Marlene, Worrell, Ernst   +5 more
core   +2 more sources

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source

Impact Activities Catalogue

TThis tool presents a selection of competences that are relevant for societal impact. The content is presented as a non-exhaustive list of competences that academics can develop for impact-oriented academic activities. Alongside each competence and its
Evaluating Societal Impact
core   +1 more source

Something new under the sun -- Office of Solar Energy Technologies [PDF]

, 2000
Three of the U.S. Department of Energy's solar technology programs are now under one umbrella: the Office of Solar Energy Technologies or the Solar Office.
National Renewable Energy Laboratory (U.S.)
core  

Study on the Impact Law of V-Shaped Gully Debris Avalanches on Double-Column Piers

Buildings
The concrete piers in steep mountain areas are highly susceptible to damage disasters due to the impact of debris avalanches, which pose a serious threat to the safe operation of bridge structures.
Mai-Li Cheng, Wen-Wei Gao
doaj   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

Multi-Response Optimization in AA6063/SS304 Bimetalic Friction Welding using Taguchi Grey Relational Analysis

Annals of "Dunarea de Jos" University of Galati, Fascicle XII, Welding Equipment and Technology
This study aimed to create a robust joint between dissimilar materials, specifically AA6063-T6 aluminium alloy and SS304 austenitic stainless steel (ASS), and optimize the parameters.
S. Senthil Murugan, M. Vishnoi, S. Kattimani, T. G. Mamatha   +3 more
doaj   +1 more source

Austempered Ductile Iron (ADI): Influence of Austempering Temperature on Microstructure, Mechanical and Wear Properties and Energy Consumption

Metals, 2018
Alloyed Ductile iron, austenitized at 840 °C for 30 min in a special sealed austempering furnace, was austempered for 30 min in molten salt mixture at 4 trial temperatures of 300 °C, 320 °C, 340 °C and 360 °C. Tensile strength, yield strength, percentage
Prabhukumar Sellamuthu, D. G. Harris Samuel, D. Dinakaran, V. P. Premkumar, Zushu Li, Sridhar Seetharaman   +5 more
doaj   +1 more source