Results 141 to 150 of about 14,305,857 (307)

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

IMPACT: Health and Welfare Division: report 2002-2003.

open access: yes, 2003
The Government published its ten-year health strategy, Quality and fairness: A health system for you, in November 2001. It contained ambitious targets to improve services and reduce inequalities with far-reaching proposals on everything from bed ...
IMPACT
core  

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Proposed alternations to shop at 357 Glenhuntly Rd., Elsternwick : sections, ceiling & roof plans

open access: yes, 1989
Commercial; shop; alternations to existing premisesPhysical format : thick stock paper; 845x600mmIncludes section and planMichael Factor, architect ; Drawn MFScale: 1:1001 ...
Factor, Michael
core  

Comparing the influence of ecology journals using citation-based indices: making sense of a multitude of metrics

open access: yesIdeas in Ecology and Evolution, 2013
The links among scholarly citations creates a tremendous network that reveals patterns of influence and flows of ideas. The systematic evaluation of these networks can be used to create aggregate measures of journal influence.
Daniel J Hocking
doaj  

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Alternations to shop at 357 Glenhuntly Rd., Elsternwick

open access: yes, 1989
Commercial; shop; alternations to existing premisesPhysical format : thick stock paper; 845x600mmIncludes plan and elevationsMichael Factor, architectScale: 1 ...
Factor, Michael
core  

The microbiome in human skin aging

open access: yesFEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana   +3 more
wiley   +1 more source

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