Results 81 to 90 of about 597,802 (215)
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Exploring the optimal impact force for chronic skeletal muscle injury induced by drop-mass technique in rats. [PDF]
Front Physiol, 2023 Ge H +9 more
europepmc +1 more source
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Zhongguo dizhi zaihai yu fangzhi xuebaoDebris flows carrying large boulders often cause more severe damage to buildings and structures than conventional debris flows. The “August 3” extreme large debris flow in Ridi gully carried large boulders, destroyed an expressway bridge, buried houses ...
Wenhao SHEN +3 more
doaj +1 more source
Genetic Algorithm Optimization of Rainfall Impact Force Piezoelectric Sensing Device, Analytical and Finite Element Investigation. [PDF]
Materials (Basel), 2023 Bani-Hani MA +3 more
europepmc +1 more source
MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
Experimental Research on a Hybrid Algorithm for Localisation and Reconstruction of the Impact Force Applied to a Rectangular Steel Plate Structure. [PDF]
Sensors (Basel), 2022 Qiu B, Lu Y, Qu X, Li X.
europepmc +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Journal of Functional Morphology and KinesiologyKarate athletes strategically use lower-limb techniques in combat, with the roundhouse kick (mawashi geri) being highly effective in kumite. To quickly improve the technical performance before training or competitions, conditioning activities (CAs) are ...
Johan Robalino +5 more
doaj +1 more source