Results 61 to 70 of about 9,443,546 (299)

Development of Low-Voltage Load Models for the Residential Load Sector [PDF]

open access: yes, 2014
A bottom-up modeling approach is presented that uses a Markov chain Monte Carlo (MCMC) method to develop demand profiles. The demand profiles are combined with the electrical characteristics of the appliance to create detailed time-varying models of ...
Kiprakis, Aristides   +6 more
core   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Impact Toolbox

open access: yes
The Impact Toolbox by the Evaluating Societal Impact project is a catalogue of tools and methods that helps university staff select resources for a structured approach to academic impact ambitions, activities and assessment.The collection draws upon a ...
Evaluating Societal Impact
core   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Impact Competence Catalogue

open access: yes
This tool presents a selection of competences that are relevant for societal impact. The content is presented as a non-exhaustive list of competences that academics can develop for impact-oriented academic activities.
Evaluating Societal Impact
core   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Energy Absorption Characteristics of PVC Coarse Aggregate Concrete under Impact Load

open access: yesInternational Journal of Concrete Structures and Materials, 2021
In this paper, polyvinyl chloride (PVC) coarse aggregate with different mixing contents is used to solve the problems of plastic pollution, low energy absorption capacity and poor damage integrity, which provides an important reference for PVC plastic ...
Shi Hu, Huaming Tang, Shenyao Han
doaj   +1 more source

Impact Activities Catalogue

open access: yes
TThis tool presents a selection of competences that are relevant for societal impact. The content is presented as a non-exhaustive list of competences that academics can develop for impact-oriented academic activities. Alongside each competence and its
Evaluating Societal Impact
core   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Study on deformation and failure law of bolt-mesh support roadway under roof impact load

open access: yesMeikuang Anquan
In order to study the deformation and failure law of bolt-mesh support roadway under roof impact load, taking 250104 transport roadway of Huating Coal Mine as background, FLAC3D was used to analyze the variation characteristics of stress, deformation and
Hongfei YANG, Zhibin LIN, Dafang YANG
doaj   +1 more source

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