Results 81 to 90 of about 8,940,064 (208)

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

Energy Consumption Characteristics and Dynamic Damage Constitutive Model of Gas-Bearing Coal under Dynamic Loading

open access: yesGaoya wuli xuebao
To explore the damage evolution law of gas-bearing coal under impact, a split Hopkinson pressure bar (SHPB) test system for gas-bearing coal was used to conduct dynamic compression tests on coal with gas pressures of 0, 0.5, 1.0, 1.5, and 2.0 MPa.
Xingang NIU
doaj   +1 more source

Building Impact Stories: An Inspirational Guide for Communicators

open access: yes
This guide is designed to assist (external) communication professionals in articulating the societal impact of university activities, projects and initiatives stemming from the university’s education, research and engagement core missions and the ...
Evaluating Societal Impact
core   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Productive Interactions (SIAMPI): A Method for Impact Assessment

open access: yes
This resource informs readers about the SIAMPI framework for impact assessment introduced by Spaapen and Van Drooge (2011), enriched with the experiences of the Evaluating Societal Impact team at EUR using the method in two case studies.
Evaluating Societal Impact
core   +1 more source

Microtab dynamic modelling for wind turbine blade load rejection [PDF]

open access: yes, 2014
A dynamic model characterising the effect of microtab deployment on the aerodynamics of its base aerofoil is presented. The developed model predicts the transient aerodynamic coefficients consistent with the experimental and computational data reported ...
Busawon, Krishna   +2 more
core   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Characteristics of deformation and failure of surrounding rock in roadway under strong impact load and control technology

open access: yesMeitan kexue jishu
In response to the challenging problem of deformation and failure of surrounding rock and support structures in roadways under rock burst, a comprehensive research approach involving numerical calculations, field measurements, and laboratory experiments ...
Yongzheng WU   +4 more
doaj   +1 more source

Greening Geographical Load Balancing [PDF]

open access: yes, 2011
Energy expenditure has become a significant fraction of data center operating costs. Recently, "geographical load balancing" has been suggested to reduce energy cost by exploiting the electricity price differences across regions.
Liu, Zhenhua
core   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

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