Results 91 to 100 of about 5,630 (304)
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
FRC Quality Inspections and Materiality Judgment
This study examines the impact of Financial Reporting Council (FRC) inspections on audit materiality decisions. Using data from listed UK companies between 2017 and 2022— following the adoption of ISA 700—we investigate whether FRC inspections ...
de Ines Anton, Omar +2 more
core +1 more source
Nonprofit Organizations as Ideal Type of Socially Responsible and Impact Investors [PDF]
, 2015 Nonprofit organizations (NPOs) as mission-driven organizations could profit from investing in stocks diametrically opposed to their mission, as they serve as a perfect hedge.
von Schnurbein, Georg, Fritz, Tizian M.
core
Zeszyty Teoretyczne RachunkowościContents / Spis treściJoanna Krasodomska, Nadia Albu, Anna Szychta, Editorial – Od Zespołu Redakcyjnego 7Mohamed Anas Belidan, Halima Baghad, Navigating materiality in sustainability reporting: A scoping review of single and double materiality approaches–
doaj +1 more source
FEBS Letters, EarlyView.Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
Materiality as spectrum and interface
, 2017 Within my studio practice, I study the impact of technology on our shifting relationship with space to address the future of materiality; acknowledging where it has been and speculating where it is headed.
Kohl, Kathleen Anne
core +1 more source
New encounters between arts and research
Akademisk Kvarter, 2016 Discussing the work of artists like Patrício Guzman, Rosângela Rennó and Teresa Margolles this article addresses the challenges that contemporary history poses for Latin and Central American artists who articulate their engagement by means of ...
Karl Erik Schøllhammer
doaj +1 more source
FEBS Letters, EarlyView.Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source
Price Impact, Materiality, and Halliburton II
, 2015 The Supreme Court decision in Halliburton Co. v. Erica P. John Fund, Inc., 134 S. Ct. 2398 (2014), reaffirmed the availability of the fraud-on-the-market presumption of “reliance” for purposes of a Rule 10b-5 class certification.
Roper, Andrew, Ferrell, Allen
core
FEBS Letters, EarlyView.This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley +1 more source