Results 121 to 130 of about 5,630 (304)
α‐Synuclein aggregation landscape from phase separation to neurotoxic intermediates
FEBS Letters, EarlyView.Alpha‐synuclein aggregation in Parkinson's disease involves a complex landscape of transient intermediates, including oligomers, fibrils and liquid–liquid phase separation (LLPS). A view is emerging in which LLPS maturation into solid‐like condensates may contribute to the formation of neurotoxic species.
Silvia Arino +2 more
wiley +1 more source
Materiality level in auditing : impact and evolution
This study aims to analyze materiality, specifically examining how auditors utilize it and the impacts and consequences it has on companies and investors.
Barros, João Pedro Fernandes
core
Athleisure: On the materiality and transgression of sports uniforms
, 2018 It could be argued that, increasingly, the individual performance of a person resides in a body that is encased in, and propelled by, the uniformed outside or clothed ‘shell’.
Craik, Jennifer
core
The Impact of Materiality, Personality Traits, and Ethical Position on Whistle-Blowing Intentions
, 2011 THE IMPACT OF MATERIALITY, PERSONALITY TRAITS, AND ETHICAL POSITION ON WHISTLE-BLOWING INTENTIONS By Karl Bryan Menk A dissertation submitted in partial fulfillment of the requirements for the degree of Doctor of Philosophy in Business at Virginia ...
Menk, Karl Bryan
core +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Impact Wear of Materials [PDF]
Journal of Applied Mechanics, 1978 Peter A. Engel, Frederick F. Ling
openaire +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Materiality and her role in the audit (external and internal)
, 2012 This thesis analyzes the materiality, as an important part of the audit. The main goal is to show the individual areas of the audit, which the materiality touches and illustrate its impact.
Špániková, Jana
core
Integrating Double Materiality : As Simple As Ticking a Box
Regulatory frameworks for sustainability reporting have become increasingly more prevalent within the EU, with the latest being CSRD. CSRD requires companies to report both impact and financial materiality, a considerable change from preceding ones.
Lindberg, Ronja, Fälth, Lisa
core +1 more source
FEBS Letters, EarlyView.Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley +1 more source