Results 141 to 150 of about 5,630 (304)
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
Molecular Oncology, EarlyView.Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source
, 2007 The materiality of virtual technologies : a new approach to thinking about the impact of multimedia in ...
Andrea Witcomb (13059759)
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Sustainability Reporting: Conception, International Approaches and Double Materiality in Action
The book provides a comprehensive exploration of the the evolution in sustainability reporting and non-financial disclosure from three perspectives: regulatory, literary, and empirical.
Agostini, Marisa +2 more
core +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Materiality and her role in the audit (external and internal)
, 2014 Diplomová práce rozebírá problematiku významnosti (materiality), jako důležité součástí auditu. Hlavním cílem práce je poukázat na jednotlivé oblasti auditu, kterých se významnost (materialita) dotýká a znázornit její vlivy.
Špániková, Jana
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Tropicality and Creative Practice: Temperature, Temperament and Temporality
eTropic: electronic journal of studies in the tropics, 2016 An exploration of materiality, corporeality and the creative tropics. The paper investigates factors affecting creative practice in the tropics, referring to the experience of the author and selected local artists and teasing out the impact on the ...
Sally Pryor
doaj
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
The materiality assessments impact of the clients' industry affiliation
, 2014 Bakgrund: Bristen på riktlinjer för väsentlighetsbedömning lämnar ett stort utrymme för revisorns professionella omdöme i väsentlighetsbedömningen. Revisorn måste använda sitt professionella omdöme vid väsentlighetsbedömningen, speciellt med hänseende ...
Dahlström, Angelina, Rosdahl, Sara
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