Results 211 to 220 of about 10,613,174 (259)

Safety and Efficacy of GLP‐1 Receptor Agonists in Adults With Epilepsy, Obesity, and Type 2 Diabetes

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Managing obesity in patients with epilepsy is complicated by the weight‐gaining properties of essential antiseizure medications (ASMs) such as valproate and pregabalin. We evaluated the safety and efficacy of initiating glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) in this population.
Hyoshin Son, Inyoung Hwang, Sang Won Lee, Yun Kim   +3 more
wiley   +1 more source

Reserves, Injury Severity, and Outcomes in Traumatic Brain Injury: A CENTER‐TBI Observational Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Reserve refers to the brain's ability to maintain function after an injury and strongly relates to traumatic brain injury (TBI) outcomes. This study examined (1) whether associations between pre‐injury reserve proxies and outcomes differed across injury severity categories, and (2) whether the impact of injury severity varied across ...
Natascha Ekdahl, Marika C. Möller, Lindsay Wilson, Anne Vik, Toril Skandsen, Jonas Stenberg, CENTER‐TBI participants and investigators   +6 more
wiley   +1 more source

Nationwide Survey of Association Between Fever and Epileptic Seizure in CDKL5 Deficiency Disorder Revealed Therapeutic Implications

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective CDKL5 deficiency disorder (CDD) is a rare, severe developmental and epileptic encephalopathy. There is a pressing need to develop effective and sustainable therapeutic strategies. We aimed to investigate the causal association between febrile episodes and epileptic seizures for therapeutic implications in CDD patients.
Siyi Wang, Jialin Du, Jinghui Liu, Dongmei Hu, Hongxin Wang, Xiaoxiao Man, Lehong Gao, Shimin Hu, Xianghong Meng, Hongyang Zhao, Minjing Hu, Yingxue Yang, Zhiqi Xiong, Liankun Ren   +13 more
wiley   +1 more source

Data‐Driven SuStaIn Model of Disability Progression in Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To determine whether ordinal Subtype and Stage Inference (SuStaIn) applied to routine ALSFRS‐R item scores can identify reproducible disability progression patterns in amyotrophic lateral sclerosis (ALS) and provide clinically meaningful staging.
Giammarco Milella, Veria Vacchiano, Vittorio Velucci, Stefano Zoccolella, Rocco Liguori, Giovanni Defazio   +5 more
wiley   +1 more source

Boundary‐Dependent Sleep–Wake Dysregulation in Idiopathic Hypersomnia

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Idiopathic hypersomnia (IH) presents with excessive daytime sleepiness (EDS) despite apparently preserved nocturnal sleep, challenging traditional models of hypersomnolence based on sleep loss or fragmentation. We aimed to test the hypothesis that EDS in IH reflects excessive stabilization of the sleep state, consistent with ...
Samantha Mombelli, Karine Lacourse, Hélène Blais, Anne‐Sophie Deshaies‐Rugama, Cynthia Thompson, Alex Desautels, Jacques Montplaisir, Milan Nigam, Christophe Moderie, Boshra Khajehpiri, Catherine Duclos, Jean Marc Lina, Julie Carrier, Nadia Gosselin   +13 more
wiley   +1 more source

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The impact of nutrition on pressure ulcer healing

British Journal of Nursing, 2022
Pressure ulcers are debilitating and often painful problem, particularly in people who are elderly, immobile and/or obese. It is estimated that more than 100 000 new pressure ulcers develop each year. These wounds are caused by friction and shear and are particularly prevalent in older people, where malnutrition can be a factor in their development ...
Sarah, Manley, Aby, Mitchell
openaire   +2 more sources

Pressures: Impact on Health of Adolescents

Pediatrics In Review, 1996
Adolescents experience a variety of daily pressures from various facets in their social environment. Their ability to deal with these pressures and the resulting stress depends on individual coping mechanisms. Stress that is induced by pressures can manifest itself as participation in risk-taking behaviors and development of poor self-concept, leading ...
W, Neal, E, Alderman
openaire   +2 more sources

Impact of Moisture on the Pressure Delivering Potential of Pressure Garments

Journal of Burn Care & Research, 2016
Pressure garments are the main method of treatment and prophylaxis for hypertrophic burn scars. The pressure they exert on the scarred skin prevents contractures forming, reduces the itchiness and pruritus associated with active hypertrophic scars, and is believed, by many, to hasten normalization of the scar tissue. The pressure exerted is believed to
Lisa, Macintyre, Monali, Dahale, Michelle, Rae   +2 more
openaire   +2 more sources

The impact of religion on men's blood pressure

Journal of Religion & Health, 1989
Most clinical studies examining the relation between religion and blood pressure status have focused on church attendance, finding lower pressures among frequent attenders. The present study examines the effect on blood pressure status of a religious meaning variable, importance of religion, both by itself and together with frequency of church ...
D B, Larson, H G, Koenig, B H, Kaplan, R S, Greenberg, E, Logue, H A, Tyroler   +5 more
openaire   +2 more sources

The impact of cross-pressures

2022
Abstract This chapter tests a key part of the theoretical argument: that the presence of group-based cross-pressure leads to a vote choice process that is less ‘constrained’. The core idea is that when long-term factors do not offer clear guidance for the vote choice, this lack of constraint will trickle down in the funnel of ...
openaire   +1 more source