Results 81 to 90 of about 26,227,955 (381)
Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu +17 more
wiley +1 more source
Impulsive Motion Inside a Cylindrical Cavity
Experimental studies of supercavitating models moving at speeds in the range from 400 m/s to 1000 m/s revealed a regime of bouncing motion, in which the rear part of an axisymmetric body periodically bounces against the free boundaries of the supercavity.
Yuriy Savchenko +2 more
doaj +1 more source
Off-forward parton distributions and impact parameter dependence of parton structure [PDF]
The connection between parton distributions as a function of the impact parameter and off-forward parton distributions is discussed in the limit of vanishing skewedness parameter $\zeta$, i.e. when the off-forwardness is purely transverse. For the $2^{nd}
Diehl +7 more
core +3 more sources
Knottin cyclization: impact on structure and dynamics [PDF]
Abstract Background Present in various species, the knottins (also referred to as inhibitor cystine knots) constitute a group of extremely stable miniproteins with a plethora of biological activities. Owing to their small size and their high stability, knottins are considered as excellent leads or scaffolds in drug ...
Laurent Chiche +11 more
openaire +4 more sources
From omics to AI—mapping the pathogenic pathways in type 2 diabetes
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan +2 more
wiley +1 more source
Multiscale Geoelectrical Properties of the Rochechouart Impact Structure, France
The 205 Ma Rochechouart impact structure (France) is characterized by various impactite formations overlying the Hercynian crystalline basement. New constraints from downhole logging and surface electrical resistivity measurements along >100 m long ...
Yoann Quesnel +6 more
doaj +1 more source
Knowing how proteases recognise preferred substrates facilitates matching proteases to applications. The S1′ pocket of protease EA1 directs cleavage to the N‐terminal side of hydrophobic residues, particularly leucine. The S1′ pocket of thermolysin differs from EA's at only one position (leucine in place of phenylalanine), which decreases cleavage ...
Grant R. Broomfield +3 more
wiley +1 more source
Impact of dynamical chiral symmetry breaking on meson structure and interactions [PDF]
We provide a glimpse of recent progress in meson physics made via QCD's Dyson-Schwinger equations with: a perspective on confinement and dynamical chiral symmetry breaking (DCSB); a pre'cis on the physics of in-hadron condensates; results for the masses ...
C. D. ROBERTS +4 more
core +2 more sources
Exploring lipid diversity and minimalism to define membrane requirements for synthetic cells
Designing the lipid membrane of synthetic cells is a complex task, in which its various roles (among them solute transport, membrane protein support, and self‐replication) should all be integrated. In this review, we report the latest top‐down and bottom‐up advances and discuss compatibility and complexity issues of current engineering approaches ...
Sergiy Gan +2 more
wiley +1 more source
Impact of DNA methylation on 3D genome structure
Determining the effect of DNA methylation on chromatin structure and function in higher organisms is challenging due to the extreme complexity of epigenetic regulation.
Diana Buitrago +14 more
semanticscholar +1 more source

