Results 171 to 180 of about 5,403,474 (293)

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Spinal Compression Fracture Mechanisms in Mountain Biking: An Accident Reconstruction Approach. [PDF]

Global Spine J
Bonte S, Olgiati G, Thouzé A, Arnoux PJ, Thollon L, Bailly N.   +5 more
europepmc   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Correction: Toxicity of tributyltin to the European flat oyster Ostrea edulis: Metabolomic responses indicate impacts to energy metabolism, biochemical composition and reproductive maturation. [PDF]

PLoS One
PLOS One Staff.
europepmc   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

Molecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero, Alejandro Belmonte‐Fernández, Mónica González‐Moreno, Laura Rodríguez‐Cordero, Begoña Pérez‐Valderrama, Joaquín Herrero‐Ruíz, Francisco Romero, Carmen Sáez, Miguel Á. Japón   +8 more
wiley   +1 more source

Three years later: tracking bothersome symptoms and impacts for people with early Parkinson's disease. [PDF]

J Neurol
Mammen JR, Reddy V, Lerner A, Shah N, Silva J, Tyo M, Magan K, Thimaikhue N, Thao-Uyen D, Solodova T, McWilliams T, Stephen M, Auinger P, Kostrzebski M, Xiao Y, Stephenson D, Adams JL.   +16 more
europepmc   +1 more source

High Impact [PDF]

British Journal of General Practice, 2019
openaire   +2 more sources

Impacted molars [PDF]

American Journal of Orthodontics and Dentofacial Orthopedics, 2020
openaire   +2 more sources

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

Molecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou, Zhen Wang, Fei Yang, Xiao Han, Lei Li, Huadong Liu   +5 more
wiley   +1 more source

Beyond diet and health: scoping umbrella review of the wider impact and influence of ultra-processed foods. [PDF]

BMC Public Health
Ullian K, Espinosa SN, Huse O, Cummins S, Medina-Lara A, Cornelsen L.   +5 more
europepmc   +1 more source