Results 141 to 150 of about 1,760,363 (317)
, 2010 This is the first investigation of Specific Language Impairment (SLI) in Gulf-Arabic (GA) speaking children. The thesis consists of two main sections, in the first one, I discuss the definitions of SLI and the various theories put forward to account for ...
Shaalan, S.
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Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Comprehension problems in children with specific language impairment: does mental imagery training help? [PDF]
, 2007 Background. Children with specific language impairment (SLI) experience story comprehension deficits (Bishop and Adams, 1992; Botting and Adams, 2005; Norbury and Bishop, 2002).
Cain, K, Joffe, V, Maric, N
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Molecular Oncology, EarlyView.Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
Transformation of Croatian Disabled Policy: Analysis of Policy Goals
Anali Hrvatskog Politološkog Društva, 2010 The article is based on the idea of transformation of the policy-making mode of Croatian disabled policy, from the medical model, through the social model to the human rights model.
Ana Petek
doaj
Supporting people with visual impairment [PDF]
, 2013 Some techniques to keep in mind when meeting with a patient with visual impairment and an verview of different models for educating children with visual and other ...
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Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
PROTOCOL: School Absenteeism Among Children and Young People With Disabilities: A Systematic Review
Campbell Systematic ReviewsThe systematic review set out in this protocol aims to identify factors influencing school absenteeism among children and young people with disabilities. The focus is on individual, family, and school‐related factors that contribute to absenteeism.
Lara Stauvermann +5 more
doaj +1 more source
Cognitive profiles of vascular and neurodegenerative MCI
, 2008 The objective of the thesis was to investigate the cognitive profiles of different types of mild cognitive impairment (MCI) and follow their course over time.
Nordlund, Arto
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