Results 131 to 140 of about 575,905 (318)

Is Language Impairments a Symptom of Nocturnal Epileptiform Activity? Studies exploring the relationship between nocturnal epileptiform activity and language impairments

, 2017
Evidence and experience indicate that children with isolated epileptiform activity during sleep (nocturnal epileptiform activity [NEA]) often have language impairments. However, this relationship is not fully understood.
Systad, Silje
core  

Phosphoinositides and inositol phosphates as molecular glues

FEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry, Alexander J. Cutright, Mong Na Claire Loi, Jessica Martin, Joseph W. Gilligan, Jakub N. Kubina, Michael J. Arambula, Susanna Tanada Palmu, Daniella Zhou, Raymond D. Blind   +9 more
wiley   +1 more source

Alzheimer’s disease and language impairments: social intervention and medical treatment

, 2015
Blanka Klimova,1 Petra Maresova,2 Martin Valis,3 Jakub Hort,4,5 Kamil Kuca6,71Department of Applied Linguistics, 2Department of Economics, Faculty of Informatics and Management, University of Hradec Kralove, 3Department of Neurology, Faculty of Medicine ...
Valis M, Kuca K, Klimova B, Hort J, Maresova P   +4 more
core  

Children's and adolescents' moral emotion attributions and judgments about exclusion of peers with hearing impairments

, 2014
Children and adolescents with hearing impairments are at risk of being excluded from activities with hearing peers. Moral emotion attributions may represent important indicators for children’s identification with the moral norm not to exclude peers based
Gasser, Luciano, Perrig-Chiello, Pasqualina, Chilver-Stainer, J., Chilver-Stainer, Jennifer, Perrig-Chiello, Pascqualina, Gassner, L.   +5 more
core   +1 more source

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

FEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara, Kinga Skoczek, Elzbieta Pyza, Milena Damulewicz   +3 more
wiley   +1 more source

Substance Abuse and Impaired Practice in Nursing [PDF]

Journal of Client-centered Nursing Care
The healthcare community is becoming increasingly concerned about the potential compromise of clinical judgment among nurses due to substance abuse. In the context of the impaired practice of nurses using substance abuse, moral responsibility has emerged
Yusrita Zolkefli
doaj  

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

The Study of the Obstructed Elements of the Blind Baseball Participating for the Visual Impairments

, 2009
[[abstract]]The aim of the study was to explore the conditions of the blind baseball participating for the visual impairments, in order to realize the establishment and operations of the blind baseball team, the motion and affect for the blind baseball ...
QIU,RE-YAO
core  

Post-stroke cognitive impairments

, 2013
Post-stroke cognitive impairments are common effects of stroke. Vascular cognitive impairments are characterized by the heterogeneity of the neuropsychological profile in relation to the site and pattern of stroke.
Elena Anatolyevna Katunina, A A Makarova, L P Belikova   +2 more
core   +1 more source

Mixed‐class J‐domain protein scaffolds promote expanded aggregate handling and multivalent Hsp70 engagement during functional disaggregase assembly

FEBS Letters, EarlyView.
Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley   +1 more source