Results 231 to 240 of about 575,905 (318)

Combined 5‐aminolevulinic acid and ferric ammonium citrate treatment promotes hair follicle growth by activating dermal papilla cells

FEBS Open Bio, EarlyView.
5‐Aminolevulinic acid combined with ferric ammonium citrate (5‐ALA/FAC) stimulates dermal papilla cell activity and promotes hair follicle growth. The treatment enhances ERK and AKT signaling, increases hair‐inductive gene expression, and restores dermal papilla function suppressed by dihydrotestosterone and oxidative stress, resulting in enhanced hair
Han‐Wook Ryu, Eok‐Soo Oh, Sewoon Kim
wiley   +1 more source

Prehabilitation for Patients with Brain Tumours: A Single-Centre Retrospective Cohort Study. [PDF]

Curr Oncol
Sun KY, Tsang DS, Langer LK, Moreno AS, Yeung AE, Tam AKH, Bayley M, Guo M.   +7 more
europepmc   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

FEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke, Michal Banasik, Rokas Juodeikis, Martin J. Warren, Richard W. Pickersgill   +4 more
wiley   +1 more source

Comparison of neuropsychological side effects between contemporary radiofrequency ablative neurosurgery for psychiatric disorders and conventional neurosurgical procedures: systematic review and meta-analysis. [PDF]

J Neurol Neurosurg Psychiatry
Vilela-Filho O, Bannach MA, Lino-Filho AM, Hamani C, Nuttin B, Hariz M, Schulder M, Greenberg BD, Cosgrove R, De Oliveira-Souza R, Horn A, Sheth SA, Kubu C, Salem S, Zaccariotti AJ, Tavares NO, Damasceno BP, Mayberg HS, Lozano AM, Visser-Vandewalle V, Kuhn J, Falkai P, Slavin K, Doshi P, Lopes AC, Vattimo EF, Coyne T, Akram H, Toda H, Halpern CH, Coenen VA, Gorgulho AA, Andrade P, Blomstedt P, Wu H, Zrinzo L, Sun B, De Quevedo JL, Belmonte-De-Abreu P, Cosyns P, Mclaughlin N, Alkhani A, Giordano J, Berk M, Yatham LN, Chabardes S, Abbadi NE, De Salles AAF, Enslin N, De Sousa MB, Oliveira JO, Labruna R, Reis AM, Jiménez-Ponce F, Ferragut MA, Chang JW, Régis J, Torres CV, Taira T, Lipsman N, Barcia JA, Rezai A, Schuurman R, Martinez-Alvarez R, Dougherty DD, Broggi G, Huys D, Bervoets C, Oliveira PM, Ragazzo PC, Giacobbe P, Lazaro-Munoz G, Polosan M, Naesström M, Johansson V, Schlaepfer T, Ribeiro TM, Lee KH, Neimat JS, Hodaie M, Sitnikov A, Yilmaz A, Almahariq F, Lopez Rios AL, Gonçalves-Ferreira A.   +84 more
europepmc   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

FEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik, Russell Pickford, Hannah C. Timmins, Olivier Piguet, Glenda M. Halliday, Matthew C. Kiernan, Woojin Scott Kim   +6 more
wiley   +1 more source

Neuropsychological effects of cannabis use by continent and age: a systematic review. [PDF]

Front Psychol
Venero-Hidalgo L, Carvajal F, Rodríguez de Fonseca F, Villanueva-Blasco VJ.   +3 more
europepmc   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Treatment Guidelines and Decision Tree for Dry Needling Musculoskeletal Conditions: A Consensus Statement. [PDF]

Int J Sports Phys Ther
Waterway T, Beougher J, Butler R, Church K, Cook G, Falsone S, Hortz B, Opitz T, Plisky PJ, Zylstra E, Martin R.   +10 more
europepmc   +1 more source

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

FEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia, Masahiro Kimura, Daisuke Kurimoto, Atsushi Sato   +3 more
wiley   +1 more source