Results 51 to 60 of about 1,312 (255)
Molecular Oncology, EarlyView.BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi +11 more
wiley +1 more source
An Overview of Carrier-based Modulation Methods for Z-Source Inverter
Power Electronics and Drives, 2019 Single-stage energy converters, in particular, the Z-Source Inverter (ZSI) or impedance source inverter, has gained significant attention in the recent years.
Roomi Muhammad M.
doaj +1 more source
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
FEBS Open Bio, EarlyView.TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose +9 more
wiley +1 more source
Identification of (20R)‐protopanaxadiol from Panax ginseng as a novel anti‐SARS‐CoV‐2 compound
FEBS Open Bio, EarlyView.We established a noninfectious BAC‐based SARS‐CoV‐2 replicon that enables antiviral screening under BSL‐2 conditions. Using this platform, we screened 373 food‐derived compounds and identified (20R)‐protopanaxadiol from Panax ginseng as a novel inhibitor of SARS‐CoV‐2 RNA replication, highlighting the value of safe replicon systems for antiviral ...
Midori Takeda +4 more
wiley +1 more source
Z‐source inverter topologies with switched Z‐impedance networks: A review
IET Power Electronics, 2021 The Z‐source inverter is one of the most interesting power electronic converters. Over the past decades, research and development have been in high demand to meet the challenges for improving the converter performance with reduced weight and cost while ...
Nafis Subhani +3 more
doaj +1 more source
Protocol for quantifying miRNA trafficking across the endosomal membrane
FEBS Open Bio, EarlyView.An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh +2 more
wiley +1 more source
Three-Phase Embedded Modified-Z-Source Three-Level T-Type Inverters
IEEE Access, 2020 Two topologies are designed by combining a modified-Z-source (MZS) network consisting of three diodes, two inductors and four capacitors to a traditional three-level T-type inverter (3LTI), and embedding either one or two dc sources in the impedance ...
Anh-Tuan Huynh, Anh-Vu Ho, Tae-Won Chun
doaj +1 more source
A high‐gain IΓ‐source hybrid single‐phase multilevel inverter for photovoltaic application
IET Power Electronics, 2021 Impedance‐based step‐up converters are widely developed for photovoltaic applications due to providing single‐stage conversion, high‐efficiency, low voltage and current stresses, and high boost‐factor. An improved Γ‐source (IΓ‐source) single‐phase hybrid
Sako Ghasimi +2 more
doaj +1 more source
Multidimensional Profiling of MRI‐Negative Temporal Lobe Epilepsy Uncovers Distinct Phenotypes
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Although hippocampal sclerosis (TLE‐HS) represents the most frequent cause of temporal lobe epilepsy (TLE), up to 30% of patients show no lesion on visual MRI inspection (TLE‐MRIneg). These cases pose diagnostic and therapeutic challenges and are underrepresented in surgical series.
Alice Ballerini +28 more
wiley +1 more source