Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
A-Source-Based Half-Bridge Inverter: Analysis, Design, and Implementation
IEEE Open Journal of the Industrial Electronics SocietyThis article introduces a new half-bridge inverter that employs Z-source technology to achieve a high boost factor without blocking high voltage on passive or active devices.
Mohammadamin Aalami +2 more
doaj +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
An Overview of Carrier-based Modulation Methods for Z-Source Inverter
Power Electronics and Drives, 2019 Single-stage energy converters, in particular, the Z-Source Inverter (ZSI) or impedance source inverter, has gained significant attention in the recent years.
Roomi Muhammad M.
doaj +1 more source
Analysis of the effect of clock drifts on frequency regulation and power sharing in inverter-based islanded microgrids [PDF]
, 2018 © 2018 IEEE. Personal use of this material is permitted. Permission from IEEE must be obtained for all other uses, in any current or future media, including reprinting/republishing this material for advertising or promotional purposes,creating new ...
Castilla Fernández, Miguel +5 more
core +2 more sources
IMPLEMENTATION OF IMPEDANCE SOURCE INVERTER SYSTEM FOR PHOTOVOLTAIC APPLICATIONS
International Journal of Power System Operation and Energy Management, 2013 This paper presents a high performance, low cost inverter for photovoltaic systems based on Impedance-source concept. Traditional Voltage-source inverter and Current-source inverter has improved to the new Z-source inverter, with a unique X-shaped network in it. This Impedance-source inverter can provide a single stage power conversion concept where as
NISHA K.C. R, T.N. BASAVARAJ
openaire +1 more source
Analysis and Simulation of Magnetically Coupled Y Shape Impedance Source Inverter
, 2016 Objectives: Proposed impedance network also has more degrees of freedom for varying its voltage gain, and hence, improving the versatility of the inverter.
C. Bharatiraja +3 more
semanticscholar +1 more source
RIPK4 function interferes with melanoma cell adhesion and metastasis
Molecular Oncology, EarlyView.RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source
Using transfer ratio to evaluate EMC design of adjustable speed drive systems [PDF]
, 2006 This paper proposes a way to evaluate the conducted electromagnetic compatibility performance of variable speed drive systems. It is considered that the measured noise level is determined by two factors, the level of the noise source and the conversion ...
Ferreira, B. +4 more
core +1 more source
Comparison of different repetitive control architectures: synthesis and comparison. Application to VSI Converters [PDF]
, 2018 Repetitive control is one of the most used control approaches to deal with periodic references/disturbances. It owes its properties to the inclusion of an internal model in the controller that corresponds to a periodic signal generator.
Costa Castelló, Ramon +1 more
core +2 more sources