Results 121 to 130 of about 778,773 (299)
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
, 2012 During the 2011 run of the LHC there was a significant measured temperature increase in the LHC Injection Kicker Magnets (MKI) during operation with 50ns bunch spacing.
Barnes, Michael +5 more
core
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Molecular Oncology, EarlyView.Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source
Impeding and Unimpeding Gamma: The Principle of Impedance
, 2000 We demonstrate that gamma (from the Lorentz transformation of the Special Theory of Relativity) acts as an impediment to velocity changes only when it occurs inside motion energy transfer relationships. We also examine whether or not gamma unimpeded velocity changes violate either the constancy of light or elementary causality.
Madore, David R., Hamilton, Gina
openaire +2 more sources
Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Molecular Oncology, EarlyView.Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source
INFLUENCE OF CONSTRUCTIVE AND TECHNOLOGICAL DEFECTS ON COAXIAL RADIO-FREQUENCY CABLE IMPEDANCE
Electrical engineering & Electromechanics, 2013 Coaxial user's radio-frequency cables belong to a category of cable television network elements parameters of which essentially specify the system capabilities as a whole.
G.V. Bezprozvannych +2 more
doaj
Investigation of sound propagation in a duct with a mean temperature gradient [PDF]
, 2014 This paper presents an analytical and numerical investigation of an impedance tube in the presence of a mean temperature gradient. Full Navier-Stokes simulation of the acoustic wave propagations through an impedance tube in the presence of a mean ...
Aygun, Haydar
core
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
A Digital Synthesis Model of Double-Reed Wind Instruments
EURASIP Journal on Advances in Signal Processing, 2004 We present a real-time synthesis model for double-reed wind instruments based on a nonlinear physical model. One specificity of double-reed instruments, namely, the presence of a confined air jet in the embouchure, for which a physical model has been ...
Guillemain Ph
doaj +1 more source