Results 101 to 110 of about 159,458 (294)
AAA+ protein unfoldases—the Moirai of the proteome
FEBS Letters, EarlyView.AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley +1 more source
Analysis of Parasitic Protozoa at the Single-cell Level using Microfluidic Impedance Cytometry
Scientific Reports, 2017 At present, there are few technologies which enable the detection, identification and viability analysis of protozoan pathogens including Cryptosporidium and/or Giardia at the single (oo)cyst level.
J. S. McGrath +5 more
doaj +1 more source
Determining detection limits of aqueous anions using electrochemical impedance spectroscopy
Journal of Analytical Science and Technology, 2017 Background Pulsed amperometric detection is a relatively new method for detection of ions and especially non-electrolytes such as carbohydrates in aqueous solutions. Pulsed amperometric detection relies on a redox reaction while electrochemical impedance
Dane W. Scott, Yahya Alseiha
doaj +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Dynamic Thermal Analysis of a Power Amplifier [PDF]
, 2006 This paper presents dynamic thermal analyses of a power amplifier. All the investigations are based on the transient junction temperature measurements performed during the circuit cooling process.
Banaszczyk, J. +5 more
core +3 more sources
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
SensorsNoise reduction is essential in analyzing electrochemical impedance spectroscopy (EIS) data for accurate parameter identification of models of electrochemical sources and interfaces.
Mitar Simić +4 more
doaj +1 more source
Turbofan noise generation and suppression in aircraft engines are reviewed. The chain of physical processes which connect unsteady flow interactions with fan blades to far field noise is addressed.
Groeneweg, J. F., Rice, E. J.
core +1 more source
On the potential of using fractional-order systems to model the respiratory impedance [PDF]
, 2006 This contribution provides an analysis of the human respiratory system in frequency domain by means of estimating the respiratory impedance. Further on, analysis of several models for human respiratory impedance is done, leading to the conclusion that a ...
De Keyser, Robain +1 more
core +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source