Results 121 to 130 of about 825,388 (293)

Simulation-Based Approach to the Matching of a Dielectric-Filled Circular Waveguide Aperture

open access: yesSensors
The circular waveguide aperture or open-end radiator, one of the canonical antenna elements, can be filled with a dielectric material for miniaturization.
Songyuan Xu   +4 more
doaj   +1 more source

Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer

open access: yesMolecular Oncology, EarlyView.
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba   +5 more
wiley   +1 more source

An Automatic Impedance Matching System

open access: yes, 1986
In systems where signals are transmitted from a source to a load, the impedance of the source can be matched to the impedance of the load. Impedance matching, in both the mechanical and the electrical sciences, has many benefits. In the electrical sense,
Eash, Matthew G.
core  

Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy

open access: yesMolecular Oncology, EarlyView.
LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir   +9 more
wiley   +1 more source

Design and operation of a load-tolerant ICRH system in Experimental Advanced Superconducting Tokamak

open access: yesNuclear Fusion
Ion Cyclotron Resonance Heating (ICRH) has been a dependable tool for sturdy plasma heating with high RF power of several megawatts. However, a sudden increase in the reflected power during ICRH heating experiments is a problem that should be solved for ...
L.N. Liu   +9 more
doaj   +1 more source

Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy

open access: yesMolecular Oncology, EarlyView.
We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley   +1 more source

Strong and wide microwave absorption of multilayered metastructure enhanced by impedance matching mechanism

open access: yesResults in Physics
The present study proposes a strong and wide microwave absorption of multilayered metastructure (SWMAMM) capable of achieving an ultra-wideband absorption of −20 dB and 60° oblique incidence. SWMAMM primarily consists of metasurface-Ⅰ (MS-Ⅰ), metasurface-
Zheyipei Ma, Yanqiong Liu, Chao Jiang
doaj   +1 more source

Small RNA pathways in mammalian oocytes

open access: yesFEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

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