Results 111 to 120 of about 825,388 (293)
Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh +11 more
wiley +1 more source
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico +5 more
wiley +1 more source
This work describes a new approach to impedance matching for ultrasonic transducers. A single matching layer with high acoustic impedance of 16 MRayls is demonstrated to show a bandwidth of around 70%, compared with conventional single matching layer ...
Harris, N.R., Qian, Yi Chen
core +1 more source
Improving APT Systems' Performance in Air via Impedance Matching and 3D-Printed Clamp. [PDF]
Liu L, Abdulla W.
europepmc +1 more source
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez +5 more
wiley +1 more source
Functional Electrical Impedance Tomography of adult and neonatal brain function. [PDF]
Electrical Impedance Tomography (EIT) is a fast, portable imaging technique that produces tomographic images of the internal impedance of an object from surface electrode measurements.
Tidswell, A.T. +1 more
core
Wideband impedance matching using Tchebycheff gain functions
A complete theoretical basis is proposed to achieve wideband impedance matching for any power line communication systems. We assume wideband impedance matching at the emission port.
Rowland, Simon; id_orcid +7 more
core +1 more source
Miniaturized Spoof Plasmonic Antennas with Good Impedance Matching. [PDF]
Ren Y +5 more
europepmc +1 more source
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault +12 more
wiley +1 more source
Determining acoustical directionality in an impedance tube using multiple fixed microphones [PDF]
Acoustic impedance of a port or object is a valuable piece of knowledge describing how well sound is transmitted or reflected. The commonly used slotted-line method is labourious and time consuming, requiring manual movement to find the maxima and minima
Scott, Jonathan B. +2 more
core

