Results 171 to 180 of about 825,388 (293)

Re‐Purposing Sapropterin (Kuvan) for ACTA2‐Related Multisystemic Smooth Muscle Dysfunction Syndrome: A Translational Mechanistic and First‐In‐Human Therapeutic Report

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Multisystemic smooth muscle dysfunction syndrome (MSMDS) is an ultra‐rare, ACTA2‐related disorder characterized by severe cerebrovascular disease, aortic aneurysms, and smooth muscle dysfunction. Using molecular dynamics simulations and in silico drug screening, we identified that sapropterin dihydrochloride (Kuvan) is a candidate capable of ...
Moran Hausman‐Kedem, Noa Bielopolski, Vijai Krishnan, Shane Wald‐Altman, Shelly I Shrian, Omer Bar‐Yosef, Livia Kapusta, Claire Shamber, Patricia L. Musolino, Miguel Weil   +9 more
wiley   +1 more source

Controllable Transformation Matching Networks for Efficient RF Impedance Matching

Efficient and controlled delivery of radio-frequency (rf) power for semiconductor plasma processing typically relies upon tunable matching networks to transform the variable plasma load impedance to a fixed impedance suitable for most rf power amplifiers.
Rafa Islam, Khandoker N
core  

Digital non-Foster-inspired electronics for broadband impedance matching. [PDF]

Nat Commun
Yang X, Zhang Z, Xu M, Li S, Zhang Y, Zhu XF, Ouyang X, Alù A.   +7 more
europepmc   +1 more source

Improved adaptive impedance matching for RF front-end systems of wireless transceivers. [PDF]

Sci Rep, 2020
Alibakhshikenari M, Virdee BS, Shukla P, See CH, Abd-Alhameed RA, Falcone F, Limiti E.   +6 more
europepmc   +1 more source

Augmenting and Assaying Nav1.1 Protein Quantity for Dravet Syndrome Therapy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Dravet Syndrome (DS) is a developmental and epileptic encephalopathy predominantly caused by heterozygous loss‐of‐function variants in SCN1A, which encodes Nav1.1. Conserved upstream open reading frames (uORFs) in SCN1A were validated to regulate translation in reporter assays, demonstrating the therapeutic viability of increasing Nav1.1 from ...
Aiswarya Saravanan, Jordan Safran, Anna Loughman, Grace Lin, Shivanshi Vaid, Dana Allababidi, Peter M. Tessier, Louis T. Dang   +7 more
wiley   +1 more source

Dual-Band 802.11 RF Energy Harvesting Optimization for IoT Devices with Improved Patch Antenna Design and Impedance Matching. [PDF]

Sensors (Basel)
Ali A, Eid R, Manaseer DE, AbuJaber HK, Ware A.   +4 more
europepmc   +1 more source

Experimental demonstration of broadband impedance matching using coupled electromagnetic resonators. [PDF]

Sci Rep, 2020
Lv X, Li C, Que Y, Li G, Hou X, Li Y, Li L, Sun Y, Guo Y.   +8 more
europepmc   +1 more source

Safety and Efficacy of GLP‐1 Receptor Agonists in Adults With Epilepsy, Obesity, and Type 2 Diabetes

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Managing obesity in patients with epilepsy is complicated by the weight‐gaining properties of essential antiseizure medications (ASMs) such as valproate and pregabalin. We evaluated the safety and efficacy of initiating glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) in this population.
Hyoshin Son, Inyoung Hwang, Sang Won Lee, Yun Kim   +3 more
wiley   +1 more source

Impedance matching in optically induced dielectrophoresis: Effect of medium conductivity on trapping force. [PDF]

Appl Phys Lett
Zaman MA, Wu M, Ren W, Hesselink L.
europepmc   +1 more source

An impedance matching algorithm for common-mode interference removal in vagus nerve recordings. [PDF]

J Neurosci Methods, 2020
Levy TJ, Ahmed U, Tsaava T, Chang YC, Lorraine PJ, Tomaio JN, Cracchiolo M, Lopez M, Rieth L, Tracey KJ, Zanos S, Zanos TP.   +11 more
europepmc   +1 more source