Results 141 to 150 of about 425,448 (355)
Harmonic Impedance Model of Multiple Utility-Interactive Multilevel Photovoltaic Inverters [PDF]
, 2022 Christian A. Rojas +4 more
openalex +1 more source
Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Molecular Oncology, EarlyView.Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source
Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
Electromechanical Impedance Model for Free 1D Thin-Walled Piezoelectric Ceramics with a Novel Derivation. [PDF]
Materials (Basel), 2020 Kong X, Chen C, Liu X, Zhu J, Qing X.
europepmc +1 more source
Modelling of the pulsatile blood flow in an arterial tree of retinal vasculature [PDF]
, 2009 This paper was presented at the 2nd Micro and Nano Flows Conference (MNF2009), which was held at Brunel University, West London, UK. The conference was organised by Brunel University and supported by the Institution of Mechanical Engineers, IPEM, the ...
2nd Micro and Nano Flows Conference (MNF2009) +3 more
core
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
发电技术Under the background of “dual carbon”, new energy sources have begun to be connected to the grid on a large scale. However, the randomness and volatility of new energy generation significantly impact the power grid, making it urgent to build a new power ...
WANG Fangfang +5 more
doaj +1 more source
Experimental validation of a two-dimensional shear-flow model for determining acoustic impedance [PDF]
Tests were conducted to validate a two-dimensional shear-flow analytical model for determining the acoustic impedance of a liner test specimen in a grazing-incidence, grazing-flow environment.
Jones, Michael G. +2 more
core +1 more source
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Reducing seat dip attenuation [PDF]
, 2000 Strategies fur reducing seat dip attenuation in concert halls are considered. It is shown that the dip is established 4 ms after the direct sound from the stage arrives at the listener.
Cox, TJ, Davies, WJ
core +1 more source