Results 221 to 230 of about 4,684 (264)

A Machine Learning-Driven Electrophysiological Platform for Real-Time Tumor-Neural Interaction Analysis and Modulation. [PDF]

Nat Commun
Xu T, Zhang X, Jiang Y, Sheng K, Li J, Ren J, He J, Liang C, Yu Z, Jin H, Zhuang B, Li L, Li N, Xu B.   +13 more
europepmc   +1 more source

Pirin Transcriptionally Regulates PLA2G4A To Inhibit Ferroptosis in Colorectal Cancer via Lipid Profile Remodeling

Advanced Science, EarlyView.
This study identifies Pirin (PIR), an iron‐binding protein, as a critical ferroptosis suppressor in colorectal cancer through lipid membrane remodeling. PIR, induced by NRF2 during ferroptotic stress, transcriptionally regulates PLA2G4A to shift cellular lipid composition away from ferroptosis‐permissive polyunsaturated phospholipids.
Wei Shi, Yue Qi Ong, Prativa Majee, Esther SM Wong, Amhed Missael Vargas Velazquez, Kerem Fidan, Pierce Kah‐Hoe Chow, Wai Leong Tam, Ker Kan Tan, Iain Beehuat Tan, Vinay Tergaonkar   +10 more
wiley   +1 more source

Recognizing the Universality of Copper Reconstruction Via Dissolution-Redeposition at the Onset of CO₂ Reduction. [PDF]

J Phys Chem Lett
Tomc B, Bele M, Plut M, Kostelec M, Popović S, Nazrulla MA, Ruiz-Zepeda F, Kamšek AR, Šala M, Elbataioui A, Rafailović LD, Pissolitto YB, Trivinho-Strixino F, Stępniowski WJ, Suhadolnik L, Hodnik N.   +15 more
europepmc   +1 more source

GOT1 Inhibition Induces Extracellular Matrix Remodeling in Pancreatic Cancer

Advanced Science, EarlyView.
Using tumor tissue engineering, we recreated pancreatic cancer and found that inhibiting glutamic‐oxaloacetic transaminase 1 (GOT1) induces extracellular matrix remodeling and secretome rewiring, as well as promotes cell death. ABSTRACT Pancreatic cancer cells rely on glutamine to sustain their survival in the stiff and poorly vascularized tumor ...
Rodrigo Curvello, Sandra Hauser, Michael Seifert, Christopher K. Barlow, Joel R. Steele, Emma Salisbury, Daniel Croagh, Kathryn S. Stok, Anna V. Taubenberger, Ralf B. Schittenhelm, Daniela Loessner   +10 more
wiley   +1 more source

Decoupling microwave heating efficiency from food property variations: A reduced-gradient index metamaterial strategy for superior efficiency and uniformity. [PDF]

Curr Res Food Sci
Yang F, Wu Y, Yang H, Chen L, Yan B, Li X, Chen X, Fan D.   +7 more
europepmc   +1 more source

Targeting IL27RA Enhances Immunotherapy in Triple‐Negative Breast Cancer by Modulating Tumor Cells and the Tumor Microenvironment

Advanced Science, EarlyView.
IL27RA upregulation drives immune evasion in TNBC by suppressing MHC‐I expression and reprogramming T/NK‐cell states, establishing an immune‐excluded tumor phenotype. Targeting this epithelial‐intrinsic IL27RA–PI3K/AKT axis offers a promising strategy to overcome immunotherapy resistance.
Jiachi Xu, Qian Long, Meirong Zhou, Qitong Chen, Jing Peng, Qingchun Liang, Danhua Zhang, Hui Zhou, Wenjun Yi   +8 more
wiley   +1 more source

Vapor Deposition Engineering for Thin-Film Microbatteries: From Nanoscale Ionics to Interface-Integrated Architectures. [PDF]

Nanomicro Lett
Zheng M, Xu X, Wang X, Lin H, Hou C, Khan M, Zhu J, Han S.   +7 more
europepmc   +1 more source

Combined Use of Microwave Sensing Technologies and Artificial Intelligence for Biomedical Monitoring and Imaging. [PDF]

Biosensors (Basel)
Martínez-Lozano A, Buitrago-Bernal A, Roy L, Vicente-Samper JM, Juan CG.   +4 more
europepmc   +1 more source

AI-Driven Polymeric Coatings: Strategies for Material Selection and Performance Evaluation in Structural Applications. [PDF]

Polymers (Basel)
Kim MO.
europepmc   +1 more source

Multifunctional Nanomaterial-Integrated Hydrogels for Sustained Drug Delivery: From Synthesis and Characterization to Biomedical Application. [PDF]

Gels
Stevanović M, Jović M, Filipović N, Lukač S, Tomić N, Popović Maneski L, Stojanović Z.   +6 more
europepmc   +1 more source