Results 131 to 140 of about 24,130 (303)
Advanced Science, EarlyView.High glucose triggers corneal endothelial dysfunction by impairing FOXO1‐mediated ITPR1 transcription, leading to disrupted mitochondria‐associated membrane (MAM) integrity and defective ER‐to‐mitochondria Ca2+ transfer. This study develops an innovative viscous DES‐AAV‐Foxo1 delivery system with enhanced transfection efficiency. This non‐invasive gene
Hongran Zhao +10 more
wiley +1 more source
Advanced Science, EarlyView.A diluent‐free, customizable liquid–liquid phase separation (LLPS) platform enables highly efficient radioactive metal ion extraction and stripping. By encapsulating hydrophobic extractants into an ionic surfactant‐rich condensed phase, this LLPS system leverages synergistic electrostatic and coordination interactions.
Ruihan Yan +7 more
wiley +1 more source
Approaches for teaching prolog to beginners [PDF]
, 2006 Prolog is a very different language compared with procedural or object-oriented languages, and developing a Prolog programming mindset is a challenge for many novices.
Joy, Mike +1 more
core
Teaching Imperative Programming With Contracts at the Freshmen Level
, 2018 We describe the experience with a freshmen-level course that teaches imperative programming and methods for ensuring the correctness of programs. Students learn the process and concepts needed to go from high-level descriptions of algorithms to correct ...
Frank Pfenning (5356877) +2 more
core +1 more source
Advanced Science, EarlyView.Two distinct slip‐link mechanisms – the slide‐ring pulley effect and highly entangled chains – are combined in a water‐rich double network hydrogel, achieving synergistic toughening, near‐complete reversibility, and exceptional friction tear resistance at >$>$91 wt.% water.
Subhankar Mandal +5 more
wiley +1 more source
An imperative programming language characterizing FBQP
, 2022 International audienceWe introduce an imperative programming language called QPT (Quantum Poly-Time) with recursion rules that captures the complexity class FBQP(Functions Bounded-error Quantum Polytime), the class of functions computable in polynomial ...
Hainry, Emmanuel +2 more
core
Tumor‐Infiltrating mregDCs Restrain Anti‐Tumor Immunity in Early Relapse HCC
Advanced Science, EarlyView.Tumor‐infiltrating mregDCs are regulated by the TNFR2‐non‐canonical NF‐κB axis, which is mediated by TNF‐α secreted by CD161+CD8+ T cells. These mregDCs recruit CD161+CD8+ T cells via the CCL20‐CCR6 axis, forming a positive feedback loop that enhances immunosuppression, promotes early recurrence of HCC, and further confirms TNFR2 as a key therapeutic ...
Zefan Zhang +13 more
wiley +1 more source
Programming by voice : Efficiency in the Reactive and Imperative Paradigm
, 2021 Due to the recent increase of computer programmers, and asa result, sufferers from Repetitive Strain Injury (RSI),programming by voice is becoming an important alternativeto keyboard-based input.
Lagergren, Miriam, Soneryd, Max
core
Advanced Science, EarlyView.This study presents a ″trash‐to‐treasure″ strategy that converts harmful joint overloads into beneficial electrical cues. The biodegradable MagPie, by providing piezoelectrical stimulation and releasing Mg2+ during mastication, exerts synergistic pro‐regenerative and anti‐inflammatory effects on Prg4+ cells via the ECM‐mediated FAK‐PI3K‐Akt axis ...
Shi‐Yang Feng +10 more
wiley +1 more source
Quantum Photothermal Self‐Monitoring Fiber Probes for In Vivo Photothermal Therapy
Advanced Science, EarlyView.A miniaturized quantum photothermal fiber probe based on a metal/polymer/glass composite optoelectronic fiber that simultaneously guides lightwave and microwave was developed for the first time. The probe achieves enhanced photothermal conversion (13°C/mW, 25°C–120°C range) while providing real‐time self‐monitoring with 0.2°C thermal resolution at the ...
Wanjun Li +12 more
wiley +1 more source