Results 121 to 130 of about 129,245 (304)

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

open access: yesFEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong   +3 more
wiley   +1 more source

Investment and abandonment decisions in the presence of imperfect aggregation of information [PDF]

open access: yes
The traditional marshallian rule of investing when the value of the investment is greater than its installment cost is modified in the presence of irreversibility and uncertainty, giving rise to an option component.
José Pablo Dapena
core  

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

open access: yesFEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin   +3 more
wiley   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

How Demand Information Can Destabilize a Cartel [PDF]

open access: yes
This paper studies a symmetric Bertrand duopoly with imperfect mon- itoring where rms receive noisy public signals about the state of demand. These signals have two opposite eects on the incentive to collude: avoid- ing punishment after a low-demand ...
Liliane Karlinger
core  

Imperfect Central Bank Communication : Information versus Distraction [PDF]

open access: yes, 2007
Much of the information communicated by central banks is noisy or imperfect. This paper considers the potential benefits and limitations of central bank communications in a model of imperfect knowledge and learning.
Dale, Spencer   +5 more
core  

Admissibility in Games with Imperfect Information

open access: yes, 2017
In this invited paper, we study the concept of admissible strategies for two player win/lose infinite sequential games with imperfect information. We show that in stark contrast with the perfect information variant, admissible strategies are only guaranteed to exist when players have objectives that are closed sets.
Brenguier, Romain   +3 more
openaire   +2 more sources

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

open access: yesFEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard   +12 more
wiley   +1 more source

Inflation Targeting Under Imperfect Knowledge [PDF]

open access: yes
A central tenet of inflation targeting is that establishing and maintaining well-anchored inflation expectations are essential. In this paper, we reexamine the role of key elements of the inflation targeting framework towards this end, in the context of ...
Athanasios Orphanides, John C. Williams
core  

Heuristic Evaluation Functions for Imperfect-Information Chess [PDF]

open access: yes, 2020
Využití evalučních funkcí v řešení her s úplnou informací vedlo k dosažení nadlidských výkonů v několika hrách, jako šachy nebo Go. V oblasti velkých her s neúplnou informací, výzkum mířil především na poker, který má dobré vlastnosti, a nové metody ...
Matěj Šesták
core  

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