Results 111 to 120 of about 129,245 (304)

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

FEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik, Russell Pickford, Hannah C. Timmins, Olivier Piguet, Glenda M. Halliday, Matthew C. Kiernan, Woojin Scott Kim   +6 more
wiley   +1 more source

Perfect Communication Equilibria in Repeated Games with Imperfect Monitoring. [PDF]

This paper introduces an equilibrium concept called perfect communication equilibrium for repeated games with imperfect private monitoring. This concept is a refinement of Myerson's [Myerson, R.B., 1982.
Tomala, Tristan
core  

Information loss associated with imperfect observation and mismatched decoding

Frontiers in Computational Neuroscience, 2011
We consider two types of causes leading to information loss when neural activities are passed and processed in the brain. One is responses of upstream neurons to stimuli being imperfectly observed by downstream neurons.
Masafumi eOizumi, Masato eOkada, Masato eOkada, Shun-ichi eAmari   +3 more
doaj   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Imperfect Central Bank Communication: Information versus Distraction [PDF]

Much of the information communicated by central banks is noisy or imperfect. This paper considers the potential benefits and limitations of central bank communications in a model of imperfect knowledge and learning.
Spencer Dale, Athanasios Orphanides, Pär Österholm   +2 more
core   +2 more sources

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source

Asset pricing with imperfect information [PDF]

, 2010
mperfect information of the participants in financial markets has been regarded as one of the important frictions which form the equilibrium in financial markets. At the heart of the discussions regarding information-related frictions, there lies the revelation of private information through the price system. Early literature such as Milgrom and Stokey
openaire   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

"Randomization, Communication and Efficiency in Repeated Games with Imperfect Public Monitoring" [PDF]

The present paper shows that the Folk Theorem under imperfect (public) information (Fudenberg, Levine and Maskin (1994)) can be obtained under much weaker set of assumptions, if we allow communication among players.
Michihiro Kandori
core  

New private information retrieval codes for imperfect privacy

ICT Express
In this paper, we introduce new codes for the private information retrieval (PIR). The conventional Tian-Sun-Chen (TSC) scheme achieves PIR capacity under the perfect privacy conditions with the minimum message length. Based on the TSC scheme, weakly PIR
Jun-Woo Tak, Sang-Hyo Kim, Yongjune Kim, Jong-Seon No   +3 more
doaj   +1 more source