Results 91 to 100 of about 129,245 (304)

Student of Games: A unified learning algorithm for both perfect and imperfect information games. [PDF]

open access: yesSci Adv, 2023
Schmid M   +12 more
europepmc   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

open access: yesMolecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel   +12 more
wiley   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

Uncertainty and Imperfect Information in Markets [PDF]

open access: yes, 2014
This chapter deals with uncertainty and incomplete information in markets. It first considers situations in which the contract proposer is the ignorant party with the problem of designing a mecha-nism that induces the counter party, who is exogenously endowed with his information, to reveal that information in such a way that maximizes the contract ...
openaire   +3 more sources

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

open access: yesMolecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi   +14 more
wiley   +1 more source

Pricing a Defaultable Zero-Coupon Bond under Imperfect Information and Regime Switching

open access: yesMathematics
We propose a pricing formula for a defaultable zero-coupon bond with imperfect information under a regime switching model using a structural form of credit risk modelling.
Ashwaq Ali Zarban   +2 more
doaj   +1 more source

REASONING WITH PROTOCOLS UNDER IMPERFECT INFORMATION

open access: yesThe Review of Symbolic Logic, 2011
We introduce and study a PDL-style logic for reasoning about protocols, or plans, under imperfect information. Our paper touches on a number of issues surrounding the relationship between an agent’s abilities, available choices, and information in an interactive situation. The main question we address is under what circumstances can the agent commit to
Pacuit, Eric, Simon, Sunil
openaire   +4 more sources

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

open access: yesMolecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski   +12 more
wiley   +1 more source

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