Results 71 to 80 of about 129,245 (304)

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Endogenous Persistence in an Estimated DSGE Model under Imperfect Information [PDF]

open access: yes
We provide a tool for estimating DSGE models by BayesianMaximum-likelihood methods under very general information assumptions. This framework is applied to a New Keynesian model where we compare the standard approach, that assumes an informational ...
Paul Levine   +3 more
core   +2 more sources

Imperfect-Recall Abstractions with Bounds

open access: yes, 2018
We develop the first general, algorithm-agnostic, solution quality guarantees for Nash equilibria and approximate self-trembling equilibria computed in imperfect-recall abstractions, when implemented in the original (perfect-recall) game. Our results are
Christian Kroer (5415797)   +1 more
core   +1 more source

Imperfect information in Reactive Modules games [PDF]

open access: yesInformation and Computation, 2018
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Julian Gutierrez 0001   +2 more
openaire   +6 more sources

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

All tests are imperfect: Accounting for false positives and false negatives using Bayesian statistics

open access: yesHeliyon, 2020
Tests with binary outcomes (e.g., positive versus negative) to indicate a binary state of nature (e.g., disease agent present versus absent) are common.
Song S. Qian   +4 more
doaj   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Imperfect Information: Experiences and Perceptions of the use of Freedom of Information in the Scottish voluntary sector [PDF]

open access: yes, 2012
First paragraph: The Freedom of Information (Scotland) Act 2002 came into effect on 1st January 2005, the same date as the wider UK legislation (Freedom of Information Act 2000 (FOIA)) also came into force.
Hutchinson, Hannah   +2 more
core  

Limited lookahead in imperfect-information games

open access: yesArtificial Intelligence, 2020
Limited lookahead has been studied for decades in perfect-information games. This paper initiates a new direction via two simultaneous deviation points: generalization to imperfect-information games and a game-theoretic approach. The question of how one should act when facing an opponent whose lookahead is limited is studied along multiple axes ...
Christian Kroer, Tuomas Sandholm
openaire   +5 more sources

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

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