Results 31 to 40 of about 22,134 (266)

A Historical Survey of Corrective and Preventive Maintenance Models with Imperfect Inspections: Cases of Constant and Non-Constant Probabilities of Decision Making

Aerospace
Maintenance strategies play a crucial role in ensuring the reliability and performance of complex systems. Imperfect inspections, characterized by the probabilities of false positives and false negatives, significantly impact the effectiveness of ...
Vladimir Ulansky, Ahmed Raza
doaj   +1 more source

The Efficacy and Safety of Bevacizumab/Irinotecan/Temozolomide (BIT) for Relapsed/Refractory Neuroblastoma: The UK Children's Cancer and Leukaemia Group Experience

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Patients with high‐risk neuroblastoma who either are refractory to induction chemotherapy or relapse following multi‐modal treatment have a dismal prognosis. Based on data from the BEACON trial, since 2021 the UK national guidelines recommend bevacizumab, irinotecan, and temozolomide (BIT) for patients with relapsed/refractory ...
Thomas J. Jackson, Menna Shamma, Upeka Senanayake, Shaimaa Sahmoud, Kathleen Duffin, Victoria Howard, David King, Ayesha Fathani, Blanche Lumb, Andrei Pobischan, Irum Latif Memon, Monzir Ahmed, Rhian Thomas, Gerard Millen, Yasmeen Alomari, Sucheta Vaidya, Lynley V. Marshall, Sally L. George, Ramya Ramanujachar, Juliet Gray, Paola Angelini   +20 more
wiley   +1 more source

Optimal Circular Economy and Process Maintenance Strategies for an Imperfect Production–Inventory Model with Scrap Returns

Mathematics, 2023
To protect our environment, current firms are committed to the circular economy and process maintenance strategies to reduce the waste of resources. In this way, they can also save costs and create an enterprise image and value.
Rung-Hung Su, Ming-Wei Weng, Chih-Te Yang, Chia-Hsuan Hsu   +3 more
doaj   +1 more source

A Transformer Maintenance Interval Optimization Method Considering Imperfect Maintenance and Dynamic Maintenance Costs

Applied Sciences
As one of the most critical components of the power grid system, transformer maintenance strategy planning significantly influences the safe, economical, and sustainable operation of the power system. Periodic imperfect maintenance strategies have become
Jianzhong Yang, Hongduo Wu, Yue Yang, Xiayao Zhao, Hua Xun, Xingzheng Wei, Zhiqi Guo   +6 more
doaj   +1 more source

An improved opportunity maintenance model of complex system

Advances in Mechanical Engineering, 2019
To solve the problems of multiple parts, high cost of disassembly, and imperfect maintenance in multi-component complex systems, an opportunistic maintenance model of multi-component complex systems based on a time threshold is proposed in this article ...
Qinghe Yuan, Zhenzhen Jin, Shun Jia, Qian Liu   +3 more
doaj   +1 more source

Goodness-of-fit tests for imperfect maintenance models based on Martingale residuals, varentropy, and probability integral transform [PDF]

Journal of Mahani Mathematical Research
In recent years, various goodness-of-fit tests have been developed to identify the underlying distribution of failure data. In this paper, we extend the application of such tests to evaluate the adequacy of imperfect maintenance models for engineering ...
Fattaneh Nezmpour, Hadi Alizadeh Noughabi, Majid Chahkandi   +2 more
doaj   +1 more source

Rapid Response to Trametinib Combined With Chemotherapy for Infant BRAF‐Fused Chiasmatic Glioma

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Infants, less than 1 year, with chiasmatic gliomas (ICG) present a major therapeutic challenge due to large tumor size, decreased vision, rapid progression, and poor response to vincristine/carboplatin chemotherapy. The majority have a BRAF fusion, which may respond to downstream MEK inhibitors but response time is slow. There are no safety or
Helen Toledano, Alexander Yelak, Walid Kaadan, Shlomo Caduri, Rivka Friedland, Orli Michaeli, Gad Dotan, Osnat Konen   +7 more
wiley   +1 more source

A Real-Time Maintenance Policy for Multi-Stage Manufacturing Systems Considering Imperfect Maintenance Effects

IEEE Access, 2018
Machines are subject to deterioration due to usage and aging. Once one machine fails, maintenance action has to be imposed in order to resume its operation. In practice, maintenance actions are not always able to restore the machine as new.
Jing Huang, Qing Chang, Jing Zou, Jorge Arinez   +3 more
doaj   +1 more source

Upacicalcet: A Novel Intravenous Calcimimetic Agent for Patients Undergoing Hemodialysis With Secondary Hyperparathyroidism

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Secondary hyperparathyroidism (SHPT) is a common complication in patients receiving maintenance dialysis, driven by calcium and phosphate metabolism disturbances. Calcimimetics are central to the management of SHPT by enhancing calcium‐sensing receptor sensitivity and reducing parathyroid hormone secretion.
Fumihiko Koiwa, Daisuke Honda, Seigo Akari, Tadao Akizawa   +3 more
wiley   +1 more source

Maintenance Modeling for a Multi-State System Under Competing Failures and Imperfect Repairs

Mathematics
A condition-based maintenance modeling approach is proposed for a multi-state system under competing failures and imperfect repairs. The system experiences three states (normal, defective and failed) over its lifecycle. Two competing failure processes, i.
Yanjing Zhang, Xiaohua Meng
doaj   +1 more source