Results 51 to 60 of about 1,587,400 (304)
A data-driven recurrent event model for system degradation with imperfect maintenance actions
Although a large number of degradation models for industrial systems have been proposed by researchers over the past few decades, the modeling of impacts of maintenance actions has been mostly limited to single-component systems.
Akash Deep, Shiyu Zhou, D. Veeramani
semanticscholar +1 more source
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Goodness-of-fit tests for imperfect maintenance models based on Martingale residuals, varentropy, and probability integral transform [PDF]
In recent years, various goodness-of-fit tests have been developed to identify the underlying distribution of failure data. In this paper, we extend the application of such tests to evaluate the adequacy of imperfect maintenance models for engineering ...
Fattaneh Nezmpour +2 more
doaj +1 more source
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Machines are subject to deterioration due to usage and aging. Once one machine fails, maintenance action has to be imposed in order to resume its operation. In practice, maintenance actions are not always able to restore the machine as new.
Jing Huang +3 more
doaj +1 more source
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
To protect our environment, current firms are committed to the circular economy and process maintenance strategies to reduce the waste of resources. In this way, they can also save costs and create an enterprise image and value.
Rung-Hung Su +3 more
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
Maintenance Modeling for a Multi-State System Under Competing Failures and Imperfect Repairs
A condition-based maintenance modeling approach is proposed for a multi-state system under competing failures and imperfect repairs. The system experiences three states (normal, defective and failed) over its lifecycle. Two competing failure processes, i.
Yanjing Zhang, Xiaohua Meng
doaj +1 more source

