Results 71 to 80 of about 1,587,400 (304)

Stochastic comparisons of imperfect maintenance models for a gamma deteriorating system [PDF]

open access: yesEuropean Journal of Operational Research, 2019
This paper compares two imperfect repair models for a degrading system, with deterioration level modeled by a non homogeneous gamma process. Both models consider instantaneous and periodic repairs.
S. Mercier, I. Castro
semanticscholar   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Imperfect Preventive Maintenance Model Study Based On Reliability Limitation

open access: yesMATEC Web of Conferences, 2016
Effective maintenance is crucial for equipment performance in industry. Imperfect maintenance conform to actual failure process. Taking the dynamic preventive maintenance cost into account, the preventive maintenance model was constructed by using age ...
Zhou Qian, Sun Yufeng
doaj   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

Maintenance Grouping Optimization for Offshore Wind Turbine Considering Opportunities Based on Rolling Horizon Approach

open access: yesPolish Maritime Research, 2018
In future, offshore wind turbines may be consider a crucial part in the supply of energy. Maintenance processes are directed to attain a safe and reliable operation of offshore machines and wind turbines.
Lua Yang   +3 more
doaj   +1 more source

Research on Existing Problems and Solutions for the Maintenance of Automated Facilities in Water Conservancy Projects [PDF]

open access: yesE3S Web of Conferences
The maintenance of automated facilities in water conservancy projects is a key link to ensure the efficient operation of water resources informatization.
Wang Tong, Ren Xuejun
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

Degradation Modeling Using Stochastic Filtering for Systems under Imperfect Maintenance

open access: yesChemical Engineering Transactions, 2013
Wiener process with a linear drift has been extensively studied in degradation modeling, mainly due to the existence of an analytical expression of the first hitting time distribution which permits feasible mathematical developments.
M. Zhang, M. Xie
doaj   +1 more source

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