Results 71 to 80 of about 1,230,707 (291)

Cost optimal maintenance in systems with imperfect maintenance

, 2016
von Dipl.-Wirtsch.-Math.
openaire   +2 more sources

Modelling and Optimizing Imperfect Maintenance of Coatings on Steel Structures [PDF]

Steel structures such as bridges, tanks and pylons are exposed to outdoor weathering conditions. In order to prevent them from corrosion they are protected by an organic coating system.
Dekker, R., Nicolai, R.P., Frenk, J.B.G.
core  

Solving the integrated production and imperfect preventive maintenance planning problem

, 2018
This paper considers the integrated production and imperfect preventive maintenance planning problem. The article provides more details on how Relax-and-Fix/Fix-and-Optimize as well as Dantzig-Wolfe Decomposition and Lagrangian Relaxation techniques were
Aghezzaf, El-Houssaine, Abdelhakim Khatab, Khatab, Abdelhakim, Le Tam, Phuoc, Phuoc Le Tam, El-Houssaine Aghezzaf   +5 more
core   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Degradation Modeling Using Stochastic Filtering for Systems under Imperfect Maintenance

Chemical Engineering Transactions, 2013
Wiener process with a linear drift has been extensively studied in degradation modeling, mainly due to the existence of an analytical expression of the first hitting time distribution which permits feasible mathematical developments.
M. Zhang, M. Xie
doaj   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens   +2 more
wiley   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

Leveraging Generative AI for Modelling and Optimization of Maintenance Policies in Industrial Systems

Information
This paper explores how generative AI can enhance the modelling and optimization of maintenance policies by incorporating real-time problem-solving techniques into structured maintenance frameworks.
Adolfo Crespo Márquez, Diego Pérez Oliver   +1 more
doaj   +1 more source

The impact of inspection errors, imperfect maintenance and minimal repairs on an imperfect production system

Mathematical and Computer Modelling, 2011
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Ya-Hui Lin, Jen-Ming Chen, Yan-Chun Chen
openaire   +3 more sources