Results 61 to 70 of about 1,230,707 (291)
Optimal Maintenance Policy for a Markov Deteriorating System Under Reliability Limit
In this study, failure data of computer numerical control machine used in defense industry was analyzed to develop maintenance algorithm with a Markov feature. An imperfect preventive maintenance model that minimizes long-term operational cost is created
Khaniyev, Tahir, Ozturk, Meltem Kocer
core +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Engineering Reports, 2022 This article develops a joint model of condition‐based maintenance (CBM) and economic production quantity (EPQ) for a single‐unit manufacturing system.
Jianhua Yang, Xiao Zhao, Mengying Han
doaj +1 more source
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
Imperfect Preventive Maintenance Model Study Based On Reliability Limitation
MATEC Web of Conferences, 2016 Effective maintenance is crucial for equipment performance in industry. Imperfect maintenance conform to actual failure process. Taking the dynamic preventive maintenance cost into account, the preventive maintenance model was constructed by using age ...
Zhou Qian, Sun Yufeng
doaj +1 more source
EAI Endorsed Transactions on Energy Web, 2020 An efficient maintenance allows extension of operating life of system, thus contributing to increase system performance. Computer systems like other systems must operate without interruption and applied strategies of maintenance must be efficiency. This
R. Oudjedi Damerdji, M. Noureddine
doaj +1 more source
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Polish Maritime Research, 2018 In future, offshore wind turbines may be consider a crucial part in the supply of energy. Maintenance processes are directed to attain a safe and reliable operation of offshore machines and wind turbines.
Lua Yang +3 more
doaj +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Research on Existing Problems and Solutions for the Maintenance of Automated Facilities in Water Conservancy Projects [PDF]
E3S Web of ConferencesThe maintenance of automated facilities in water conservancy projects is a key link to ensure the efficient operation of water resources informatization.
Wang Tong, Ren Xuejun
doaj +1 more source