Results 121 to 130 of about 26,368 (244)

Biomimetic Zirconia Abutment for Single Implant Supported Restoration: A Case Report [PDF]

, 2015
Sadid-Zadeh Ramtin
openalex   +1 more source

Tumor and germline testing with next generation sequencing in epithelial ovarian cancer: a prospective paired comparison using an 18‐gene panel

Molecular Oncology, EarlyView.
Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard, Cristina Mitric, Melanie Care, Tracy L. Stockley, Raymond H. Kim, Jeanna McCuaig, Blaise Clarke, Laura Ranich, Clare Sheen, Sarah E. Ferguson, Liat Hogen, Taymaa May, Marcus Q. Bernardini   +12 more
wiley   +1 more source

Biomechanical Performance of Implant-Tooth-Supported Prostheses: A Numerical 3D Finite Element Analysis

International Dental Journal
: Objective: To assess the biomechanical behaviour of implant-tooth-supported (hybrid) prostheses, compared with an implant-implant-supported prosthesis, utilising two different prosthetic materials, employing finite element analysis (FEA).
Hatem S. Sadek, Noha M. Anany, Mohamed I. El-Anwar, Abdulaziz Alhotan, Al-Hassan Diab, Bassma R. Fayad, Islam M. Heiba, Islam G. Shahin, Christoph Bourauel, Tarek M. Elshazly   +9 more
doaj   +1 more source

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

Molecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece, Giulio Lovato, Ilaria Cela, Arianna Mercatelli, Benedetta Ferro, Jussi Nikkola, Sara Pagotto, Tommaso Grottola, Vincenzo De Laurenzi, Rossella Cicchetti, Antonio Marchetti, Luigi Schips, Rossano Lattanzio, Stefano Iacobelli, Emily Capone, Peter Black, Mads Daugaard, Michele Marchioni, Gianluca Sala   +18 more
wiley   +1 more source

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source

Assessment Of Intraoral Scanning For Three-Unit Implant-Supported Bridges

International Dental Journal
Aim or purpose: To evaluate the dimensional accuracy of intraoral scanning (IOS) for three-unit implant-supported fixed prostheses in posterior regions and compare it with conventional impression methods to determine its clinical applicability. Materials
Shuobo Fang, Zhong Xingjian, Wu Xueying, Shen Yuyin, Gong Zhicheng   +4 more
doaj   +1 more source

Evaluation of marginal bone loss in implant supported over-dentures

, 2022
Haripal Singh, Karthika Janardhan, G. Jeevan Kumar, Mohammed Ibrahim, Damarasingu Rajesh, Atul Aggarwal   +5 more
openalex   +2 more sources

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

Preventing LVAD implantation by early short-term mechanical support and prolonged inodilator therapy [PDF]

, 2014
Jasper J. Brugts, Olivier C. Manintveld, Alina A. Constantinescu, Dirk W. Donker, Robert J. van Thiel, Koen Nieman, Lucia S.D. Jewbali, Felix Zijlstra, Kadir Çalişkan   +8 more
openalex   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source