Results 151 to 160 of about 26,368 (244)

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

Molecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone, James Dunford, Eleanor Calcutt, Vicki Gamble, Filiz Senbabaoglu Aksu, Lorena Ligammari, Georgina Wherry, Giorgia Gaeta, John C. Christianson, Adrienne M. Flanagan, Udo Oppermann, Adam P. Cribbs   +11 more
wiley   +1 more source

Optimization of Implantable Axial Pump to Increase Efficiency of Mechanical Circulatory Support

, 2017
S. V. Gautier, А. П. Кулешов, А. Е. Efimov, И. И. Агапов, G. P. Itkin   +4 more
openalex   +2 more sources

Simulation of installing transitional implant dentures under a support of dental bridge prototypes for the two-stage dental implant osteointegration period [PDF]

, 2016
Т.В. Полякова, С.С. Гаврюшин, С Д Арутюнов   +2 more
openalex   +1 more source

Implant Prosthetic Rehabilitation of the Patients with Mandibular Resection Following Oral Malignoma Surgery [PDF]

, 2012
Patient underwent mandibular resection due to surgical therapy of oropharingeal malignoma. Facial asymmetry and cosmetic distortion are frequent consequences of such interventions, which may also include deviation and intrusion of the mandible, motor and
Ivone Uhač, Marica Šimunović-Šoškić, Mirna Juretić, Robert Antonić, Robert Cerović, Sonja Pezelj-Ribarić, Zoran Kovač   +6 more
core   +1 more source

Transcriptional regulation of neuropeptide receptors underlies context‐dependent adaptation in Drosophila melanogaster

FEBS Open Bio, EarlyView.
Under environmental changes, the expression level of neuropeptide (NP) and neuropeptide receptor (NPR) genes changes to confer context‐dependent adaptation to the model organism Drosophila melanogaster. Through finding more regulatory elements in the NPR genes in comparison with their ligands (NPs), we found that NPR‐biased transcriptional regulation ...
SeungHeui Ryu, Yanan Wei, Zekun Wu, Tianmu Zhang, DoHoon Lee, Hadi Najafi, Woo Jae Kim   +6 more
wiley   +1 more source

The role of the European Union Support in implantation the provisions of the National Environmental Policy in years 2004-2006

, 2010
Bartosz Bartniczak
openalex   +2 more sources

Effect of T-scan Occlusal Analysis and Adjustment Versus Articulating Paper on Stresses Transmitted to Single Mandibular Implant Supported Prosthesis

, 2023
mohammed saud, Mahmoud Alafandy, Ahmed Mohamed Osama, Omar Abbas El-Sadat   +3 more
openalex   +2 more sources

Biomechanical finite element analysis of short-implant-supported, 3-unit, fixed CAD/CAM prostheses in the posterior mandible [PDF]

, 2022
Lana Zupancic Cepic, Martin Frank, Andreas Reisinger, Dieter H. Pahr, Werner Zechner, Andreas Schedle   +5 more
openalex   +1 more source

Electrical pulse stimulation reflecting the episodic nature of real‐life exercise modulates metabolic and secretory profile of primary human myotubes

FEBS Open Bio, EarlyView.
Here, we introduced an intermittent electrical stimulation protocol mimicking the episodic nature of real‐life exercise in vitro by alternating low‐ and high‐frequency stimulation. In comparison with widely used continuous stimulation, it enhanced the rate of glucose and fatty acid oxidation, but not the myokine release.
Klára Gabrišová, Tímea Kurdiová, Daria Barkova, Natália Pálešová, Jana Babulicová, Silvia Tyčiaková, Marta Novotová, Mária Balážová, Miroslav Sabo, Václav Pustka, Jozef Ukropec, Barbara Ukropcová   +11 more
wiley   +1 more source

Direct Transference of Emergence Profile in Implant Supported Fixed Bridges [PDF]

, 2016
Óscar Figueras-Álvarez
openalex   +1 more source