Results 101 to 110 of about 483,999 (304)

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Evaluating implant properties on the implant stability of immediately loaded implants

Bioinformation
Immediate implantation of dental implants provides a shortened period of treatment at the cost of high stability requirements. Therefore, it is of interest to assess the impact of implant diameter, length and surface texture on the implant stability quotient (ISQ) of 40 patients on fibroblastic posterior mandibular implants.
Ahmed, Md Kafeel, Mangat, Harinder Singh, Bhargava, Ananya, Tanwar, Monika, Jayaprakash, Mugur Basavanna, Das, Satyabrata, Mehta, Miral, Singh, Dhirendra Kumar   +7 more
openaire   +2 more sources

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Ability of modal analysis to detect osseointegration of implants in transfemoral amputees : a physical model study [PDF]

, 2013
Owing to the successful use of non-invasive vibration analysis to monitor the progression of dental implant healing and stabilization, it is now being considered as a method to monitor femoral implants in transfemoral amputees.
Cairns, Nicola, Pearcy, Mark, Adam, Clayton, Smeathers, James   +3 more
core   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

O uso de guias no planejamento das próteses sobre implantes [PDF]

, 2014
TCC (graduação) - Universidade Federal de Santa Catarina. Centro de Ciências da Saúde. Odontologia.O protocolo para o sucesso de um implante deve resultar na osseointegração, e, ao mesmo tempo, no posicionamento ideal do implante para a confecção de uma ...
Dias, Madalena Lucia Pinheiro
core  

A multifactorial analysis to identify predictors of implant failure and peri-implant bone loss

, 2015
Aim. To identify risk factors for failure and bone loss of implants in a large study sample on the basis of multivariate analyses. Materials and Methods.
Vervaeke, Stijn,, Cosyn, Jan,, Bruno Collaert, Deschepper, Ellen,, Stijn Vervaeke, Cosyn, Jan, Hugo De Bruyn, Deschepper, Ellen, Collaert, Bruno,, Ellen Deschepper, De Bruyn, Hugo, Jan Cosyn, Collaert, Bruno, De Bruyn, Hugo,, Vervaeke, Stijn   +14 more
core   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

Nutritional Effects of Implant Therapy in Edentulous Patients-A Systematic Review

, 2015
Purpose: The aim of this study was to present all the relevant studies that have evaluated, with valid scientific methodology, the possible physical and nutrient intake improvement of edentulous subjects rehabilitated with removable and supported or ...
Lagravere, MO, Sanchez-Ayala, A, Goncalves, TMSV, Lucena, SC, Barbosa, CMR   +4 more
core   +1 more source