Results 141 to 150 of about 2,067,546 (336)

Effect of chemotherapy on passenger mutations in metastatic colorectal cancer

Molecular Oncology, EarlyView.
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui, Matthew A. Cottam, Muhammad Bilal Mirza, Keeli B. Lewis, Kristen K. Ciombor, Mary Kay Washington, Kamran Idrees   +6 more
wiley   +1 more source

Targeted long-read nanopore sequencing as a complementary approach for detecting STRC variants and distinguishing the STRCP1 pseudogene

Scientific Reports
The stereocilin (STRC) gene is a significant contributor to mild-to-moderate sensorineural hearing loss (SNHL), particularly in cases of biallelic STRC deletions and copy number alterations.
Hideaki Moteki, Shin-ya Nishio, Shin-ichi Usami   +2 more
doaj   +1 more source

Combining Perfluorobutylpentane (F₄H₅) with Glaucoma Drainage Device Implantation for Silicone Oil-Induced Glaucoma: A Pilot Study

, 2023
Stylianos Kandarakis, Petros Petrou, Spyridon Doumazos, Konstantina Chronopoulou, Leonidas Doumazos, Ioannis Halkiadakis, Ilias Georgalas   +6 more
openalex   +1 more source

Strength through diversity: how cancers thrive when clones cooperate

Molecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken, Maartje Witsen, Emile E. Voest, Krijn K. Dijkstra   +3 more
wiley   +1 more source

Taper wear in total joint arthroplasty can be reliably assessed with various coordinate measuring systems

Scientific Reports
In total joint arthroplasty, wear and corrosion at modular taper junctions is an issue with clinical implications, as ions and wear debris can lead to adverse tissue reactions.
Therese Bormann, Ulrike Mueller, Robert Sonntag, Stefan Schroeder, J. Philippe Kretzer   +4 more
doaj   +1 more source

Accuracy of digital guided implant surgery: expert consensus on nonsurgical factors and their treatments

口腔疾病防治
The standardized workflow of computer-aided static guided implant surgery includes preoperative examination, data acquisition, guide design, guide fabrication and surgery. Errors may occur at each step, leading to irreversible cumulative effects and thus
XU Shulan, LI Ping, YANG Shuo, LI Shaobing, LU Haibin, ZHU Andi, HUANG Lishu, WANG Jinming, XU Shitong, WANG Liping, TANG Chunbo, ZHOU Yanmin, ZHOU Lei   +12 more
doaj   +1 more source

Comparison of osseointegration in piezoimplants versus cylindrical implants [PDF]

, 2019
BACKGROUND: Dental implants have been successful for the restoration of edentulous areas, but current techniques are inadequate in areas lacking sufficient bone volume. Piezoelectric surgery has shown encouraging effects on both osseous healing.
Fujinaka, Trevor
core  

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

Molecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié, Umberto Malapelle, Catherine Alix‐Panabières, Claus Lindbjerg Andersen, Sandra Chlebowski, Vivien Lake, Caroline Lacoux, Virginie Lespinet‐Fabre, Olivier Bordone, Simon Heeke, Christophe Bontoux, Ellen Heitzer, Klaus Pantel, Paul Hofman   +13 more
wiley   +1 more source

Accuracy and precision of an intraoral scanner in complex prosthetic rehabilitations: an in vitro study [PDF]

, 2017
The main purpose of this study is to measure the accuracy and the precision of the intraoral optical scanner CS3500® (Carestream Dental LLC, Atlanta, USA) in complex clinical situations as full arch rehabilitations on impl ants.
BRAUNER, EDOARDO, DE ANGELIS, FRANCESCA, DI CARLO, Stefano, PICCOLI, Luca, PIGNATIELLO, GIUSEPPE, POMPA, Giorgio   +5 more
core  

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source