Results 151 to 160 of about 2,067,546 (336)

Neuro-electronic technology in medicine and beyond [PDF]

, 2000
This dissertation looks at the technology and social issues involved with interfacing electronics directly to the human nervous system, in particular the methods for both reading and stimulating nerves.
Ward, Jamie A
core  

Bioactive Glass Coated Zirconia for Dental Implants: a review

, 2020
Kaiqiang Zhang, Quyet Van Le
openalex   +2 more sources

Intralipid infusion at time of embryo transfer in women with history of recurrent implantation failure: A systematic review and meta‐analysis [PDF]

, 2021
Michael P. Rimmer, Naomi Black, Stephen D. Keay, Siobhan Quenby, Bassel H. Al Wattar   +4 more
openalex   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Roles of VWA1 and Rac2 in compensatory and decompensatory responses via FGF9/FGFR3 and p38 MAPK signaling pathways in condylar chondrocytes under distinct mechanical stress

Arthritis Research & Therapy
Background/purpose Few studies paid attention to compensatory and decompensatory responses of condylar cartilage under different mechanical conditions and the underlying mechanism.
Yuqi Liu, Fangwen Jia, Kangya Li, Chao Liang, Yanxi Li, Wei Geng   +5 more
doaj   +1 more source

How does age affect outcomes after left ventricular assist device implantation: results from the PCHF‐VAD registry [PDF]

, 2022
Sumant P. Radhoe, Jesse F. Veenis, Nina Jakuš, Philippe Timmermans, Anne–Catherine Pouleur, Paweł Rubiś, Emeline M. Van Craenenbroeck, Edvinas Gaizauskas, Eduardo Barge‐Caballero, Stefania Paolillo, Sebastian Grundmann, Domenico D’Amario, Oscar Ö. Braun, Aggeliki Gkouziouta, Ivo Planinc, Jure Samardžić, Bart Meyns, Walter Droogné, Karol Wierzbicki, Katarzyna Holcman, Andreas J. Flammer, Hrvoje Gašparović, Bojan Biočina, Lars H. Lund, Davor Miličić, Frank Ruschitzka, Maja Čikeš, Jasper J. Brugts   +27 more
openalex   +1 more source

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

Molecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute, Júlia Huguet‐Pradell, Jordi Abril‐Fornaguera, Albert Gris‐Oliver, Alex Rialdi, Elisa Fernández‐Martínez, Carla Montironi, Vanessa Del Pozo, Peter Houghton, Laura Zanatto, Agavni Mesropian, Ieva Keraite, Swan Thung, Carolina Armengol, Pau Sancho‐Bru, Ernesto Guccione, Roser Pinyol, Josep M. Llovet   +17 more
wiley   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

Molecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair   +17 more
wiley   +1 more source

Management and outcome of vagus nerve stimulator implantation: experience of an otolaryngeal/neuropediatric cooperation [PDF]

, 2021
Stefan Grasl, Stefan Janik, A. Dressler, Robert Diehm, Gudrun Gröppel, Katy Eichinger, M. Grasl, Wolfgang Gstœttner, Martha Feucht, Erich Vyskocil, Wolf‐Dieter Baumgartner   +10 more
openalex   +1 more source

Monitoring of circulating tumor DNA allows early detection of disease relapse in patients with operable breast cancer

Molecular Oncology, EarlyView.
Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad, Marie Austdal, Oddmund Nordgård, Gunnar Mellgren, Satu Oltedal, Marie L. Austbø, Ylva H. Vignes, Thomas Helland, Kristin Jonsdottir, Tone H. Lende, Emilius A. M. Janssen, Bjørnar Gilje, Kjersti Tjensvoll, PBCB study group, Gunnar Mellgren, Tone Hoel Lende, Anette Heie, Kristin Viste, Anita Røyneberg Alvheim, Emiel AM Janssen, Kristin Jonsdottir, Ann Cathrine Kroksveen, Thomas Helland, Einar Gudlaugsson, Oddmund Nordgård, Satu Oltedal, Kristin Løge Aanestad, Jan Terje Kvaløy, Kirsten Lode, Kari Britt Hagen, Marie Austdal, Ylva H. Vignes, Siri Tungland Sola, Nina Egeland Amundsen, Finn Magnus Eliassen, Emeritus Ernst A Lien   +35 more
wiley   +1 more source