Results 41 to 50 of about 107,419 (261)

The clinical relevance of fixation failure after pubic symphysis plating for anterior pelvic ring injuries: an observational cohort study with long-term follow-up

Patient Safety in Surgery
Background Open reduction and plate fixation is a standard procedure for treating traumatic symphyseal disruptions, but has a high incidence of implant failure.
Dmitry Notov, Eva Knorr, Ulrich J.A. Spiegl, Georg Osterhoff, Andreas Höch, Christian Kleber, Philipp Pieroh   +6 more
doaj   +1 more source

Natural Killer Cells in Paediatric Soft Tissue Sarcomas: A Systematic Review

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Paediatric soft tissue sarcomas (pSTS) are a rare and heterogeneous group of malignant tumours arising in tissues of mesenchymal origin. The role of natural killer (NK) cells in pSTS remains poorly understood, with evidence fragmented across small preclinical studies and early‐phase clinical trials.
Raya Dean, Lara V. Graham, Christina Putnam, Rosa Gomes Alves Martins, Daniel T. Harding, Tim J. Underwood, Zoë S. Walters, Matthew D. Blunt   +7 more
wiley   +1 more source

Effect of plaque accumulation and occlusal overload on peri-implant bone loss

Journal of Biological Research, 2017
This paper presents a case report where the influence of plaque accumulation and overload on a dental implant was observed. The patient presented crown loss on one implant affected by peri-implant bone resorption and gingival inflammation associated with
Elena Dellepiane, Maria Menini, Paolo Canepa, Paolo Pera   +3 more
doaj   +1 more source

Smoking, radiotherapy, diabetes and osteoporosis as risk factors for dental implant failure: a meta-analysis. [PDF]

PLoS ONE, 2013
BACKGROUND: There are conflicting reports as to the association between smoking, radiotherapy, diabetes and osteoporosis and the risk of dental implant failure.
Hui Chen, Nizhou Liu, Xinchen Xu, Xinhua Qu, Eryi Lu   +4 more
doaj   +1 more source

Failure rates and factors associated with infrazygomatic crestal orthodontic implants - A prospective study

Journal of Oral Biology and Craniofacial Research, 2023
Objective: Infrazygomatic crestal (IZC) implants have gained increased popularity over the past few years. Hardly any studies have been done to assess the rate and reasons for failure of IZCs.
Gauri Gill, Keerthan Shashidhar, M.N. Kuttappa, Dhyan Kushalappa P B, Gautham Sivamurthy, Soham Mallick   +5 more
doaj   +1 more source

On Hierarchical Composite Endpoints in Pediatric Cancer Supportive Care: Illustrative Examples From Two Multi‐Center Phase‐III Randomized Clinical Trials

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric supportive care clinical trials often involve multiple clinically important outcomes, complicating trial interpretation. Hierarchical composite endpoints (HCEs) provide a framework to integrate key outcomes according to clinical importance.
Willem H. Collier, Mark Zobeck, Adam J. Esbenshade, Christopher C. Dvorak, Lillian Sung, David Freyer, Sarah Alexander, Etan Orgel, Nicole J. Ullrich, Zach Prudowsky, Brian Fisher, Caitlin W. Elgarten   +11 more
wiley   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Failure modes of patellofemoral arthroplasty—registries vs. clinical studies: a systematic review

Acta Orthopaedica, 2019
Background and purpose — Patellofemoral arthroplasty (PFA) has been debated since early studies showed poor implant survival. Recent studies show better results. This review reports failure modes for PFA and investigates differences in data reported from
Nikolaj B Bendixen, Peter W Eskelund, Anders Odgaard   +2 more
doaj   +1 more source

Implantable Sensors for Heart Failure [PDF]

Circulation: Arrhythmia and Electrophysiology, 2010
Heart failure (HF) affects more than 5 million Americans, and acute decompensated heart failure (ADHF) has emerged as the leading cause of hospitalization among people over the age of 65 years.1 Importantly, HF is a leading public health concern, and hospitalization expenses related to management of ADHF impose a substantial financial burden on the ...
Faisal M, Merchant, G William, Dec, Jagmeet P, Singh   +2 more
openaire   +2 more sources

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source