Results 1 to 10 of about 106,854 (254)

RO8191, a new compound for initiating embryo implantation in mice [PDF]

Scientific Reports
During early pregnancy in mice, leukemia inhibitory factor (LIF) regulates embryo implantation by activating the JAK/STAT3 signaling pathway. The STAT3 pathway has been recognized to play a critical role in embryo implantation; however, it remains ...
Junlan Shu, Jumpei Terakawa, Sota Takikawa, Satoko Osuka, Ayako Muraoka, Jiali Ruan, Atsuo Iida, Junya Ito, Eiichi Hondo   +8 more
doaj   +3 more sources

Role of Vascular Endothelial Growth Factor (VEGF) in Human Embryo Implantation: Clinical Implications

Biomolecules, 2021
Vascular endothelial growth factor (VEGF) is a well-known angiogenic factor that plays a critical role in various physiological and pathological processes.
Xi Guo, Hong Yi, Tin Chiu Li, Yu Wang, Huilin Wang, Xiaoyan Chen   +5 more
doaj   +3 more sources

Role of circadian clock in female embryo implantation [PDF]

Frontiers in Cell and Developmental Biology
Accumulating evidence indicates that circadian rhythm disruption can exert an impact on female reproductive function. In the context of female reproduction, the success of embryo implantation is of utmost significance as it is an essential process for ...
Yukai Zhou, Yukai Zhou, Xiaodie He, Xiaodie He, Zhenxin Chen, Zhenxin Chen, Yucong Gou, Kaixin Zhou, Jinrong Huang, Mei Chen, Jin Hong, Lei Gao, Lei Gao   +12 more
doaj   +2 more sources

Uterine receptivity, embryo attachment, and embryo invasion: Multistep processes in embryo implantation

Reproductive Medicine and Biology, 2019
Background Recurrent implantation failure is a critical issue in IVF‐ET treatment. Successful embryo implantation needs appropriate molecular and cellular communications between embryo and uterus.
Yamato Fukui, Yasushi Hirota, Mitsunori Matsuo, Mona Gebril, Shun Akaeda, Takehiro Hiraoka, Yutaka Osuga   +6 more
doaj   +2 more sources

Enhancing uterine receptivity for embryo implantation through controlled collagenase intervention [PDF]

Life Science Alliance
A safe and effective enzymatic pretreatment in mice enhances embryo implantation, revealing how remodeling of specific matrix components of the uterus facilitates implantation through distinct molecular mechanisms without any risk, holding clinical ...
Eldar Zehorai, Tamar Gross Lev, Elee Shimshoni, Ron Hadas, Idan Adir, Ofra Golani, Guillaume Molodij, Ram Eitan, Karl E Kadler, Orit Kollet, Michal Neeman, Nava Dekel, Inna Solomonov, Irit Sagi   +13 more
doaj   +2 more sources

Analysis of factors related to embryo implantation/clinical pregnancy in patients with severe Intrauterine Adhesions(IUA) undergoing In Vitro Fertilization-Embryo Transfer (IVF-ET) following hysteroscopic adhesiolysis: a retrospective study [PDF]

BMC Pregnancy and Childbirth
Purpose To investigate factors influencing embryo implantation and clinical pregnancy in patients with severe IUA undergoing IVF-ET and to develop a predictive model.
Jiao Lin, Xingping Zhao, Yuxi Chen, Bing Xie, Haiying Cheng, Sang He, Chen Luo, Xiaoyan Cheng, Bingyu Li, Enuo Peng, Xianghong Huang   +10 more
doaj   +2 more sources

Endometrial stromal cells of women with recurrent miscarriage fail to discriminate between high- and low-quality human embryos [PDF]

, 2012
Background The aetiology of recurrent miscarriage (RM) remains largely unexplained. Women with RM have a shorter time to pregnancy interval than normally fertile women, which may be due to more frequent implantation of non-viable embryos.
AJ Wilcox, AM Musters, Annemieke Kavelaars, B Gellersen, Birgit Gellersen, Charlotte H. E. Weimar, Cobi J. Heijnen, Cornelis B. Lambalk, CW Redman, DK Gardner, E Vanneste, EB Baart, G Teklenburg, G Teklenburg, GM Stirrat, H Carp, HJ Leese, HJ Leese, HM Picton, IC Lakovschek, Jan J. Brosens, JD Aplin, JL Evers, Johanna M. T. de Vreeden-Elbertse, M Bielanska, M Gonzalez, M Salker, N Mansouri-Attia, Nick S. Macklon, NS Macklon, PJ Stokes, R Rai, RM Popovici, S Grewal, S Grewal, S Quenby   +35 more
core   +21 more sources

Endometrial stromal cell miR-19b-3p release is reduced during decidualization implying a role in decidual-trophoblast cross-talk

Frontiers in Endocrinology, 2023
IntroductionA healthy pregnancy requires successful blastocyst implantation into an adequately prepared or ‘receptive’ endometrium. Decidualization of uterine endometrial stromal fibroblast cells (hESF) is critical for the establishment of a healthy ...
Ellen Menkhorst, Ellen Menkhorst, Teresa So, Teresa So, Kate Rainczuk, Siena Barton, Siena Barton, Wei Zhou, Wei Zhou, Tracey Edgell, Evdokia Dimitriadis, Evdokia Dimitriadis, Evdokia Dimitriadis   +12 more
doaj   +1 more source

Intrauterine administration of peripheral blood mononuclear cells (PBMCs) improves embryo implantation in mice by regulating local Treg/Th17 cell balance

The Journal of Reproduction and Development, 2021
Immune imbalance of Treg/Th17 cells may contribute to recurrent implantation failure (RIF) during in vitro fertilization and embryo transfer (IVF-ET). In this study, we sought to determine the effect of intrauterine administration of mouse PBMCs prior to
Lei FAN, Menghan SHA, Wei LI, Qingling KANG, Jianli WU, Suhua CHEN, Nan YU   +6 more
doaj   +1 more source

Autophagy as a Therapeutic Target of Natural Products Enhancing Embryo Implantation

Pharmaceuticals, 2021
Infertility is an emerging health issue worldwide, and female infertility is intimately associated with embryo implantation failure. Embryo implantation is an essential process during the initiation of prenatal development.
Hyerin Park, Minkyoung Cho, Yoonju Do, Jang-Kyung Park, Sung-Jin Bae, Jongkil Joo, Ki-Tae Ha   +6 more
doaj   +1 more source