Results 21 to 30 of about 106,854 (254)

Human Blastocyst Secreted microRNA Regulate Endometrial Epithelial Cell Adhesion

EBioMedicine, 2015
Successful embryo implantation requires synchronous development and communication between the blastocyst and the endometrium, however the mechanisms of communication in humans are virtually unknown.
Carly Cuman, Michelle Van Sinderen, Michael P. Gantier, Kate Rainczuk, Kelli Sorby, Luk Rombauts, Tiki Osianlis, Evdokia Dimitriadis   +7 more
doaj   +1 more source

The effects of aging on molecular modulators of human embryo implantation

iScience, 2021
Summary: Advancing age has a negative impact on female fertility. As implantation rates decline during the normal maternal life course, age-related, embryonic factors are altered and our inability to monitor these factors in an unbiased genome-wide ...
Panagiotis Ntostis, Grace Swanson, Georgia Kokkali, David Iles, John Huntriss, Agni Pantou, Maria Tzetis, Konstantinos Pantos, Helen M. Picton, Stephen A. Krawetz, David Miller   +10 more
doaj   +1 more source

Hormonal Replacement Treatment for Frozen-Thawed Embryo Transfer With or Without GnRH Agonist Pretreatment: A Retrospective Cohort Study Stratified by Times of Embryo Implantation Failures

Frontiers in Endocrinology, 2022
ObjectiveTo evaluate the efficacy of the long-acting gonadotropin-releasing hormone agonist (GnRH-a) administration before hormone replacement treatment for frozen-thawed embryo transfer in women with different times of embryo implantation failures ...
Leizhen Xia, Lifeng Tian, Shanshan Zhang, Jialyu Huang, Qiongfang Wu   +4 more
doaj   +1 more source

Secreted MicroRNA to Predict Embryo Implantation Outcome: From Research to Clinical Diagnostic Application

Frontiers in Cell and Developmental Biology, 2020
Embryo implantation failure is considered a leading cause of infertility and a significant bottleneck for in vitro fertilization (IVF) treatment. Confirmed factors that lead to implantation failure involve unhealthy embryos, unreceptive endometrium, and ...
Wei Zhou, Wei Zhou, Evdokia Dimitriadis, Evdokia Dimitriadis   +3 more
doaj   +1 more source

The Complicated Effects of Extracellular Vesicles and Their Cargos on Embryo Implantation

Frontiers in Endocrinology, 2021
As a rate-limiting step in pregnancy, embryo implantation is highly dependent on intercellular communication. Extracellular vesicles (EVs) are newly identified to be important in the course of intercellular communication.
Nan-Xing Jiang, Nan-Xing Jiang, Xue-Lian Li, Xue-Lian Li   +3 more
doaj   +1 more source

Uterine selection of human embryos at implantation [PDF]

, 2014
Human embryos frequently harbor large-scale complex chromosomal errors that impede normal development. Affected embryos may fail to implant although many first breach the endometrial epithelium and embed in the decidualizing stroma before being rejected ...
A Mertzanidou, B Cloke, B Crespi, BC Han, BM Forman, CH Weimar, D Emera, D Emera, D Haig, DM Benbrook, E Rajcan-Separovic, E Vanneste, EB Chuong, EM Heijnen, FU Hartl, G Teklenburg, GW Wong, H Yang, HH Kampinga, JJ Brosens, JJ Brosens, LA Kazal, M Furuhashi, M Iwaki, M Ohmuraya, M Salker, MD Stephenson, MS Salker, MS Salker, N Arimura, N Mansouri-Attia, N Sharma, N Sharma, NS Macklon, P Walter, R Rai, S Altmae, S Kaushik, S Quenby, T Iwawaki, T Kadowaki, Y Kabeya, YC Ruan, YH Yang, YJ Kim   +44 more
core   +2 more sources

Uterine luminal-derived extracellular vesicles: potential nanomaterials to improve embryo implantation

Journal of Nanobiotechnology, 2023
Most pregnancy losses worldwide are caused by implantation failure for which there is a lack of effective therapeutics. Extracellular vesicles are considered potential endogenous nanomedicines because of their unique biological functions.
Linjun Hong, Xupeng Zang, Qun Hu, Yanjuan He, Zhiqian Xu, Yanshe Xie, Ting Gu, Huaqiang Yang, Jie Yang, Junsong Shi, Enqin Zheng, Sixiu Huang, Zheng Xu, Dewu Liu, Gengyuan Cai, Zicong Li, Zhenfang Wu   +16 more
doaj   +1 more source

Assessment of Embryo-Induced Transcriptomic Changes in Hamster Uterus Using RNA-Seq

Cellular Physiology and Biochemistry, 2018
Background/Aims: The mouse is widely used as an animal model for studying human embryo implantation. However, the mouse is unique in that both ovarian progesterone and estrogen are critical to implantation, whereas in the majority of species (e.g.
Ming-Yu Huang, Wen-Qian Zhang, Miao Zhao, Can Zhu, Jia-Peng He, Ji-Long Liu   +5 more
doaj   +1 more source

Prediction model for day 3 embryo implantation potential based on metabolites in spent embryo culture medium

BMC Pregnancy and Childbirth, 2023
Background Metabolites in spent embryo culture medium correlate with the embryo’s viability. However, there is no widely accepted method using metabolite dada to predict successful implantation.
Rong Liang, Sheng Nan Duan, Min Fu, Yu Nan Chen, Ping Wang, Yuan Fan, Shihui Meng, Xi Chen, Cheng Shi   +8 more
doaj   +1 more source

Assisted reproductive technology in the USA: is more regulation needed? [PDF]

, 2014
The regulation of assisted reproductive technologies is a contested area. Some jurisdictions, such as the UK and a number of Australian states, have comprehensive regulation of most aspects of assisted reproductive technologies; others, such as the USA ...
Adamson, Allen, ASRM, ASRM, ASRM, ASRM and SART Practice Committee, ASRM Ethics Committee, ASRM Office of Public Affairs, Basu, Cahn, Cahn, Centers for Disease Control and Prevention, Centers for Disease Control and Prevention, Centers for Disease Control and Prevention, Centers for Disease Control and Prevention, Centers for Disease Control and Prevention, Centers for Disease Control and Prevention, Chambers, Cohen, Conrad, D'Orazio, De Neubourg, England and Wales High Court, Eric Blyth, Food and Drug Administration, Gleicher, Gleicher, Gürtin, Hamilton, Heled, HFEA, HFEA, HFEA, HFEA, HFEA, HFEA, Isley, Johnson, Jones, Jungheim, Kalfoglou, Keel, Kushnir, Lewis, Lim, Lucy Frith, Macaldowie, Martin, Ory, Rebar, Sawyer, Sims, Spar, Sunderam, Sylvester, The National Conference of State Legislatures, The National Conference of State Legislatures, The National Conference of State Legislatures, The National Conference of State Legislatures, Tobin, Washington   +60 more
core   +1 more source