Results 71 to 80 of about 107,386 (261)

Implant failure after ankle arthrodesis versus total ankle arthroplasty: a matched- cohort study

open access: yesJournal of the Foot & Ankle
Objective: To compare the risk of implant failure between ankle arthrodesis and total ankle arthroplasty using propensity score matching and time-to-event analysis.
Cláudia Diniz Freitas   +3 more
doaj   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

open access: yesFEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji   +2 more
wiley   +1 more source

Dentists’ Perspectives on Defining Failure in Implant-Prosthodontic Therapy: A Cross-Sectional Study

open access: yesApplied Sciences
Aim: to investigate the criteria to define implant–prosthodontic therapy failure for dentists in Croatia. Methods: We conducted a cross-sectional study using an online questionnaire among dentists in Croatia.
Mare Kovic   +6 more
doaj   +1 more source

Evaluation of Failure Rate for Cortical Dental Implants Placed in the Mandibular Anterior Region: A Systematic Review [PDF]

open access: yesJournal of Clinical and Diagnostic Research
Introduction: To enhance the success of dental implants, it is crucial to understand the factors contributing to implant failure. Practitioners should carefully evaluate the relevance and impact of critical risk factors associated with the mandibular ...
Srishty Goyal   +3 more
doaj   +1 more source

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

open access: yesFEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin   +3 more
wiley   +1 more source

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

open access: yesFEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill   +6 more
wiley   +1 more source

Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model

open access: yesFEBS Open Bio, EarlyView.
This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito   +7 more
wiley   +1 more source

Artificial Intelligence and Mental Well‐Being in Adult Education: Implications for Practice and Professional Responsibility

open access: yesNew Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Mental well‐being is central to adult learner success, yet many adult education institutions lack capacity to provide timely and accessible support. This article examines how artificial intelligence (AI) can strengthen mental health–adjacent supports in adult and continuing higher education, with attention to professional practice and ...
Adam L. McClain, Thomas Wade
wiley   +1 more source

Implant failure after ankle arthrodesis versus total ankle arthroplasty: a propensity score – matched multicenter retrospective cohort study

open access: yesJournal of the Foot & Ankle
Introduction: End-stage ankle arthritis is a debilitating condition often requiring surgical treatment when conservative measures fail. Ankle arthrodesis and total ankle arthroplasty are the two principal operative options; however, comparative data on ...
Cláudia Diniz Freitas
doaj   +1 more source

Early dental implant failure in patient associated with oral bisphosphonates

open access: yesIndian Journal of Dental Research, 2012
Oral bisphosphonates are routinely prescribed to post menopausal women. These have shown to increase the risk of osteonecrosis. However, this action may be augmented by local factors.
Ridhimaa Gupta
doaj   +1 more source

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