Results 71 to 80 of about 2,414,398 (303)

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

Immediate dental implants: insights into early and late failures from a large-scale Chinese cohort

BMC Oral Health
Background Immediate implant placement (IIP) has emerged as a time-efficient therapeutic approach in dentistry, offering advantages such as reduced treatment duration and improved alveolar bone preservation.
Yiyun Yang, Lu Zhou, Xiaomei Hong, Mingfu Ye, Yang Yang, Xiaoling Deng, Mingyan Xu   +6 more
doaj   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

Molecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim, Maryam Aslam, Elouise Torruella, Alphons Sony, Asif Rahman, Simira Smith, Columba de la Parra, Moira Sauane   +7 more
wiley   +1 more source

Implantation Failure

, 2017
The purpose of this paper is to show the usefulness of an alternative scientific argument based on Transcurssive Logic in the natural science, such as medicine. The auxiliary methodology was applied to determine the role of a polyvalent endometrial treatment in patients suffering from ‘repeated implantation failure’ in an ovodonation program. Secondly,
Tersoglio, A. E., Salatino, D.R.
openaire   +2 more sources

Implantable Sensors for Heart Failure [PDF]

Circulation: Arrhythmia and Electrophysiology, 2010
Heart failure (HF) affects more than 5 million Americans, and acute decompensated heart failure (ADHF) has emerged as the leading cause of hospitalization among people over the age of 65 years.1 Importantly, HF is a leading public health concern, and hospitalization expenses related to management of ADHF impose a substantial financial burden on the ...
Faisal M, Merchant, G William, Dec, Jagmeet P, Singh   +2 more
openaire   +2 more sources

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

Assessing the Impact of Dental Implant Length on Early Failure Rates: A Retrospective Analysis

Journal of Pharmacy and Bioallied Sciences
Introduction: The selection criteria of implant is very critical. Implant length determines the mechanics of osseointegration. Objective: To investigate the influence of dental implant length on early failure rates, osseointegration success, peri-implant
Bhuvaneshwari Karthikeyan, K Hanumantha Kumar, K. Sadananda, Inderjit Murugendrappa Gowdar, Shital J. Sonune, Doaa Abdelaziz A. Helal   +5 more
doaj   +1 more source

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

Molecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira, Ana Teixeira‐Marques, Rui Freitas, João A Carvalho, Sara Monteiro‐Reis, Giorgio I. Russo, Rui Henrique, Carmen Jerónimo   +7 more
wiley   +1 more source

Ailing and Failing Implant: Initial Therapy and Management

RUHS Journal of Health Sciences
Dental implants are frequently utilized to restore both parţial and total dentures. Dental implant failure is not unusual, despite the fact that numerous studies on the subjects have documented a long-term success rate.
Natwar Singh, Sharmistha Vijay, Neha Saini, Anil Kumar, Kanika Singhal
doaj   +1 more source

Influence of a single preoperative dose of antibiotics on the early implant failure rate. A randomized clinical trial

, 2019
Background The use of a preoperative single dose of antibiotics as routine in conjunction with implant surgery is controversial, in light of the unclear effect on early implant failure rate and risk for development of resistant bacterial strains. Purpose
Jack Hilon, Hilon, Jack,, Friberg, Bertil,, Mahdi Hasan Rasoul, Rasoul, Madi Hasan,, Hossein Kashani, Kashani, Hossein,, Bertil Friberg   +7 more
core   +1 more source