Results 91 to 100 of about 1,869,696 (253)

Assessing the Impact of Dental Implant Length on Early Failure Rates: A Retrospective Analysis

open access: yesJournal of Pharmacy and Bioallied Sciences
Introduction: The selection criteria of implant is very critical. Implant length determines the mechanics of osseointegration. Objective: To investigate the influence of dental implant length on early failure rates, osseointegration success, peri-implant
Bhuvaneshwari Karthikeyan   +5 more
doaj   +1 more source

Overcoming single dental implant failure using two small implant support for one crown: five year retrospective study

open access: yes, 2020
Introduction Overcoming a dental implant failure/osseo-disintegration is still a dilemma for implantologists. Using two implants to support for one crown is a novel approach to resolve this issue.
Doan, N.   +7 more
core   +1 more source

Paying for treatments? Influences on negotiating clinical need and decision-making for dental implant treatment [PDF]

open access: yes, 2009
Background: the aim of this study is to examine how clinicians and patients negotiate clinical need and treatment decisions within a context of finite resources.
May, Carl   +50 more
core   +2 more sources

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

open access: yesMolecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic   +10 more
wiley   +1 more source

Influence of Prognostic Risk Indicators on Osseointegrated Dental Implant Failure: A Matched Case-Control Analysis

open access: yes, 2012
Dental implant treatment is an important therapeutic modality with documented long-term success for replacement of missing teeth. However, dental implants can be susceptible to disease conditions or healing complications that may lead to implant loss ...
Rami Alissa, Richard J. Oliver
core   +1 more source

Fractography of a neck failure in a double-modular hip implant [PDF]

open access: yes, 2014
: The tapered joints of modular hip implants are prone to fretting and crevice-corrosion. This can lead to total failure in under a year, especially for heavier, more active implant recipients.

core   +1 more source

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

open access: yesMolecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira   +7 more
wiley   +1 more source

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

open access: yesMolecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico   +5 more
wiley   +1 more source

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

open access: yesFEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill   +6 more
wiley   +1 more source

Implant failure after ankle arthrodesis versus total ankle arthroplasty: a matched- cohort study

open access: yesJournal of the Foot & Ankle
Objective: To compare the risk of implant failure between ankle arthrodesis and total ankle arthroplasty using propensity score matching and time-to-event analysis.
Cláudia Diniz Freitas   +3 more
doaj   +1 more source

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