Results 71 to 80 of about 1,869,696 (253)

Recurrent implantation failure: definition [PDF]

open access: yesJournal of Assisted Reproduction and Genetics, 2007
An attempt to define recurrent implantation failure.Literature review.Numerous definitions of recurrent implantation failure exist. The complexity and redundancy of the process of implantation makes a single definition difficult to determine.Each center must establish a definition of recurrent implantation failure based upon the data from that center ...
openaire   +2 more sources

Fatigue Reliability of 3 Single-Unit Implant-Abutment Designs

open access: yes, 2012
Objectives: Because the mechanical behavior of the implant-abutment system is critical for the longevity of implant-supported reconstructions, this study evaluated the fatigue reliability of different implant-abutment systems used as single-unit crowns ...
Coelho, Paulo G.   +6 more
core   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Removal of failed dental implants revisited: Questions and answers

open access: yesClinical and Experimental Dental Research, 2019
Objectives This narrative review is aiming on showing reasons for implant failure, removal techniques, and respective clinical considerations; further, the survival rate of implants in previous failed sites is examined.
Alex Solderer   +5 more
doaj   +1 more source

Implant failures and age at the time of surgery: A retrospective study on implant treatment in 2915 partially edentulous jaws

open access: yes, 2019
Purpose: To further report and analyze data on the prevalence of implant failures related to age at surgery in partially edentulous jaws. Materials and Methods: Altogether, 2915 partially edentulous jaws (Kennedy Class I and II) were consecutively ...
Jemt, Torsten,, Torsten Jemt
core   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

Implant Failure Predictors in the Posterior Maxilla: A Retrospective Study of 273 Consecutive Implants

open access: yes, 2008
Background: The goal of this study was to retrospectively analyze a cohort of 136 patients who underwent dental implant placement in the posterior maxilla at the University of Connecticut Health Center to assess and identify predictors for implant ...
Huynh-Ba, Guy   +7 more
core   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

open access: yesMolecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Clinical consequences early implant failures of IL-1 genotype on early implant failures in patients under periodontal maintenance

open access: yes, 2005
Background: Implant failure and biologic complications such as periimplantitis are not completely avoidable. Are there any genetic and microbiologic parameters that Could be used to identify patients at risk for implant failure, preferably prior to ...
De Bruyn, HugoGE36UZGent0000705496158010018893350000-0003-0200-9546F73EAFBC-F0ED-11E1-A9DE-61C894A0A6B4   +8 more
core   +1 more source

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