Results 41 to 50 of about 89,381 (262)

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Photobiomodulation Effect on Implant Stability in Immediate Implant in the Maxillary Premolars. A Prospective Cases Series. [PDF]

Alexandria Dental Journal
Background: Evidence on the use of low-level laser photobiomodulation in immediate implant placement is limited. The study aimed at describing the outcomes of low-level laser biostimulation for immediate implant placement in the maxillary premolars zone ...
basma kassem, saeda osman, yehia el-mahallawy   +2 more
doaj   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source

Comparison of Implant Stability Using Resonance Frequency Analysis: Osteotome versus Conventional Drilling

Frontiers in Dentistry, 2016
Objectives: Implant primary stability is one of the important factors in achieving implant success. The osteotome technique may improve primary stability in patients with poor bone quality. The aim of this study was to compare implant stability using two
Rokhsareh Sadeghi, Amir Reza Rokn, Asghar Miremadi   +2 more
doaj  

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Factors Influencing Resonance Frequency Analysis (RFA) Measurements and 5-Year Survival of Neoss Dental Implants

International Journal of Dentistry, 2019
Background. Diagnostic instruments based on resonance frequency analysis (RFA) can be utilised to assess dental implant stability during treatment and follow-up. Aim.
Peter Andersson, Luca Pagliani, Damiano Verrocchi, Stefano Volpe, Herman Sahlin, Lars Sennerby   +5 more
doaj   +1 more source

The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source

The Relationship Between Peri-Implant Marginal Bone Loss and Resonance Frequency Analysis

Journal of Functional Biomaterials
Resonance frequency analysis (RFA) has been used as a diagnostic method to measure implant stability at all stages of healing. In addition to evaluating the status of the peri-implant marginal bone, it can also indicate the most appropriate time to load ...
Esteban Pérez-Pevida, Iván Monteagudo-Villalobos, David Chávarri-Prado, Alejandro Estrada-Martínez, Miguel Beltrán-Guijarro, Markel Diéguez-Pereira, Aritza Brizuela-Velasco   +6 more
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source