Results 51 to 60 of about 89,381 (262)

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Resonance frequency analysis

open access: yesIndian Journal of Dental Research, 2011
Initial stability at the placement and development of osseointegration are two major issues for implant survival. Implant stability is a mechanical phenomenon which is related to the local bone quality and quantity, type of implant, and placement ...
Rajiv K Gupta, Thallam V Padmanabhan
doaj   +1 more source

Comparison of primary stability in craniofacial implant with V-shape and buttress thread design in goat skull using resonance frequency analysis

open access: yesIndian Journal of Dental Research, 2020
Background and Aims: To find out the primary stability in maxillofacial implant with two different thread designs. Methods: Two group of implants were selected for the study – Group I maxillofacial implant with V-shape thread, and Group II implant with ...
Karthikeyan Ramkumar   +4 more
doaj   +1 more source

A new endodontic stabilizer implant device

open access: yesThe Journal of Prosthetic Dentistry, 1991
A new endodontic stabilizer implant device is presented that can be used immediately after enucleation of large periapical cysts. The force transmission characteristics of this implant were evaluated by means of photoelasticity. The implant served to distribute incisal forces within the supporting structure.
Fragiskos, F.   +3 more
openaire   +3 more sources

Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers

open access: yesFEBS Letters, EarlyView.
Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui   +4 more
wiley   +1 more source

Comparative Evaluation of Osseodensification vs Conventional Osteotomy Technique for Dental Implants: A Systematic Review and Meta-analysis [PDF]

open access: yesInternational Journal of Prosthodontics and Restorative Dentistry
Purpose: This systematic review and meta-analysis was conducted to evaluate the efficiency of the osseodensification protocol over the conventional drilling protocol.
Pooja S Poonia, Ina B Patel
doaj   +1 more source

Prospecting the protein design landscape

open access: yesFEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona   +4 more
wiley   +1 more source

RNA‐related functions of BRCA2 in transcription, replication, and genome stability

open access: yesFEBS Letters, EarlyView.
Beyond its role in homologous recombination, BRCA2 regulates R‐loop homeostasis, DNA–RNA hybrid resolution, RNA polymerase II dynamics, and transcriptional activation. Disruption of any of these functions can contribute to genome instability, inflammatory signaling, and tumorigenesis. BRCA2 is a central tumor suppressor protein best known for its roles
Lucia Alvaro‐Aranda   +2 more
wiley   +1 more source

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

open access: yesFEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux   +7 more
wiley   +1 more source

Influence of bony defects on implant stability

open access: yesClinical Oral Implants Research, 2010
AbstractIntroduction: The purpose of this study was to analyze the evolution of implant mechanical stability in different types/sizes of bony defects using both Periotest and Osstell devices as “objective tools.”Materials and methods: Thirty‐two implants were randomly allocated to one of the four types of bone defects: marginal bone loss, peri‐apical
Merheb, Joe   +4 more
openaire   +4 more sources

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