Results 131 to 140 of about 86,432 (312)

Oral factor Xa inhibitors for stroke prevention in patients with device-detected atrial fibrillation – Recent evidence from the NOAH-AFNET 6 and ARTESiA trials

open access: yesCardiologia Hungarica
Device-detected atrial fibrillation (AF), also known as atrial high rate episodes, is a frequent finding in patients with a cardiac implantable electronic device such as a pacemaker, or an implantable cardioverter-defibrillator or loop recorder.
Alexander P. Benz, William F. McIntyre
doaj   +1 more source

Risk Stratification for Sudden Cardiac Death In Patients With Non-ischemic Dilated Cardiomyopathy [PDF]

open access: yes, 2005
Non ischemic dilated cardiomyopathy (NIDCM) is a disorder of myocardium. It has varying etiologies. Albeit the varying etiologies of this heart muscle disorder, it presents with symptoms of heart failure, and rarely as sudden cardiac death (SCD ...
Ghosh, Joydeep   +3 more
core   +1 more source

Impact of severe periodontitis and diabetes mellitus on recurrent cardiovascular outcomes

open access: yesJournal of Periodontology, EarlyView.
Abstract Background This post hoc analysis of the Periodontitis and Coronary Heart Disease study (ClinicalTrials.gov Identifier: NCT01045070) aimed to determine the association between diabetes and recurrent cardiovascular events (CVEs) in patients with cardiovascular disease (CVD) and severe periodontitis.
Stefan Reichert   +3 more
wiley   +1 more source

Jervell and Lange‐Nielsen Syndrome Related Clinical Genetics and Experimental Models

open access: yesPediatric Discovery, EarlyView.
ABSTRACT Jervell and Lange‐Nielsen syndrome (JLNS) is defined by electrocardiographic QT prolongation and sensorineural hearing loss, caused by homozygous or compound heterozygous variants in KCNQ1 and/or KCNE1. KCNQ1 encodes the alpha subunit Kv7.1 of the ion channels accountable for slow delayed rectifier potassium currents (IKs), whereas KCNE1 ...
Yafei Zhou   +3 more
wiley   +1 more source

A novel selective stabilizer of the ryanodine receptor 2 prevents stress‐induced ventricular arrhythmias without impairing cardiac function

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Aberrant activation of type 2 ryanodine receptors (RyR2) causes lethal arrhythmias, such as catecholaminergic polymorphic ventricular tachycardia (CPVT). Developing drugs that suppress RyR2 hyperactivation may be key to novel arrhythmia treatments.
Nagomi Kurebayashi   +29 more
wiley   +1 more source

An implantable cardioverter defibrillator in a patient with triple mechanical valves

open access: yesClinical Case Reports, 2018
Key Clinical Message A patient with permanent atrial fibrillation, triple mechanical prosthetic valve replacements, and nonischemic cardiomyopathy presented with symptomatic high‐grade atrioventricular block.
Alex W. X. Tan   +3 more
doaj   +1 more source

Predictors of Late Mortality in D‐Transposition of the Great Arteries After Atrial Switch Repair: Systematic Review and Meta‐Analysis

open access: yesJournal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2019
Background Existing data on predictors of late mortality and prevention of sudden cardiac death after atrial switch repair surgery for D‐transposition of the great arteries (D‐TGA) are heterogeneous and limited by statistical power.
Prashanth Venkatesh   +14 more
doaj   +1 more source

Prognostic Value of Small Coved‐Type ST‐Segment Area in Patients With Spontaneous Type 1 Brugada Syndrome

open access: yesJournal of Cardiovascular Electrophysiology, EarlyView.
Electrical and structural abnormalities in Brugada syndrome lead to a smaller coved‐type ST‐segment area. A reduced ST‐segment area may identify patients at elevated risk of ventricular fibrillation. ABSTRACT Background Risk stratification in Brugada syndrome (BrS) remains challenging.
Nario Sano   +10 more
wiley   +1 more source

Intelligence-based medicine [PDF]

open access: yes, 2009
Despite seven hundred thousand new medical references last year, the relationship between a given set of medical features and specific pathophysiology, treatment, and criteria of improvement is often weak.
Didier Journois, Pierre Squara
core   +1 more source

Efficacy and Safety of Dronedarone in Overweight and Obesity: Post Hoc Analysis of the ATHENA Trial

open access: yesJournal of Cardiovascular Electrophysiology, EarlyView.
ABSTRACT Introduction Obesity represents a prevalent condition with multiple comorbidities, including atrial fibrillation (AF). Dronedarone, an antiarrhythmic drug (AAD), has demonstrated efficacy in patients with paroxysmal/persistent AF and cardiovascular (CV) risk factors.
Mate Vamos   +3 more
wiley   +1 more source

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