Results 171 to 180 of about 34,514 (296)

When Trabeculations Disrupt Conduction: Left Ventricular Noncompaction Presenting With Symptomatic Bradycardia and Isorhythmic Dissociation

open access: yesClinical Case Reports, Volume 14, Issue 6, June 2026.
ABSTRACT In young patients with unexplained symptomatic bradycardia, LVNC should be considered even when initial echocardiography is equivocal. Precise ECG interpretation is essential—AV dissociation driven by a ventricular escape rhythm must be distinguished from true AV block, as this distinction directly determines whether cardiac MRI, genetic ...
Talha Shamshad   +7 more
wiley   +1 more source

Cardiac Arrest as the First Manifestation of Single Coronary Artery—Potential Role of FFRCT for Detecting Critical Flow Reduction. A Case Report

open access: yesClinical Case Reports, Volume 14, Issue 6, June 2026.
ABSTRACT Single coronary artery may present with life‐threatening ventricular arrhythmias even in the absence of structural heart disease or inducible ischemia. FFR‐CT can detect clinically relevant flow reduction despite normal functional testing, highlighting its potential role in risk stratification in patients with coronary anomalies.
Frantisek Nehaj   +7 more
wiley   +1 more source

Sheath Rupture in Figure‐Of‐Eight Suturing: A Case Report and Risk Reduction Strategies

open access: yesClinical Case Reports, Volume 14, Issue 6, June 2026.
Risk reduction strategies for sheath rupture during figure‐of‐eight suturing include appropriate needle placement, controlled suture tension, avoidance of proximal sheath puncture, use of polyether block amide sheaths, and retention of an intraluminal device during suturing.
Takahiro Kobayashi   +7 more
wiley   +1 more source

From Molecules to Machines: An Integrative Framework Linking Molecular Pathogenesis, Multi‐Factorial Risk, Risk Stratification, Clinical Management, and Artificial Intelligence in QT Prolongation and Sudden Cardiac Death

open access: yesClinical Cardiology, Volume 49, Issue 6, June 2026.
An integrative conceptual framework linking the five principal domains addressed in this review. Beginning at the molecular level, loss‐of‐function mutations in KCNQ1 and KCNH2 reduce outward repolarizing currents (IKs and IKr), while gain‐of‐function SCN5A mutations augment late inward sodium current (INa), establishing the genetic substrate for ...
Mojtaba Farjam   +2 more
wiley   +1 more source

T‐Cell Acute Lymphoblastic Leukemia in a Young Patient With Andersen–Tawil Syndrome Successfully and Safely Treated With Intensive Chemotherapy Including Potential Precipitating Drugs: A Case Report After 3.5 Years of Follow‐up

open access: yeseJHaem, Volume 7, Issue 3, June 2026.
ABSTRACT Andersen–Tawil syndrome (ATS) is a rare, hereditary channelopathy characterized by periodic paralysis, cardiac arrhythmias, and sometimes developmental anomalies. No association with hematologic malignancies has previously been reported. We describe the case of a 27‐year‐old man with genetically confirmed Type 1 ATS who developed T‐cell acute ...
Ramy Rahmé   +6 more
wiley   +1 more source

Real‐World Diagnostic Workup of Patients Suspected for Light Chain Amyloidosis and Wild‐Type Transthyretin Amyloid Cardiomyopathy: A Retrospective Cohort Study Using US Electronic Health Records

open access: yeseJHaem, Volume 7, Issue 3, June 2026.
ABSTRACT Introduction Light chain (AL) amyloidosis and transthyretin amyloid cardiomyopathy (ATTR‐CM) are the most common types of cardiac amyloidosis. Despite similar manifestations, prognosis and treatments are distinct, emphasizing the importance of accurate and timely diagnosis. This retrospective cohort study assessed real‐world diagnostic workups
Muhamed Baljevic   +7 more
wiley   +1 more source

Resistant to Ablation, Responsive to Hydroquinidine: Precision Medicine Guides Recovery in MEPPC Syndrome Cardiomyopathy

open access: yesJournal of Arrhythmia, Volume 42, Issue 3, June 2026.
We report a case of MEPPC syndrome presenting with severe dilated cardiomyopathy due to a pathogenic SCN5A p.Arg814Trp variant. Genetic diagnosis enabled precision pharmacotherapy with hydroquinidine, which suppressed multifocal Purkinje‐origin ectopy resistant to catheter ablation and led to marked improvement in left ventricular function.
Jonathan L. Ciofani   +2 more
wiley   +1 more source

Preservation of an extravascular implantable cardioverter-defibrillator during sternotomy and surgical myectomy. [PDF]

open access: yesHeartRhythm Case Rep
Collings S   +6 more
europepmc   +1 more source

Feasibility and Safety on Left Bundle Branch Area Pacing With Standard Stylet‐Driven Lead: ACHIEVE‐SYNC Multicenter Prospective Observational Cohort Study

open access: yesJournal of Arrhythmia, Volume 42, Issue 3, June 2026.
In the prospective multicenter study, left bundle branch area pacing using stylet‐driven pacing leads demonstrated a high procedural success rate and showed stable lead performance during long‐term follow‐up. ABSTRACT Background Right ventricular pacing increases the risk of dyssynchrony, which raises the need for more physiological pacing strategies ...
Ga‐In Yu   +12 more
wiley   +1 more source

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